Schäfer Hans Hendrik, Sudano Isabella, Theus Gian-Reto, Noll Georg, Burnier Michel
Chris Barnard Division of Cardiothoracic Surgery, University of Cape Town, Groote Schuur Hospital, 7925 Cape Town, South Africa.
Blood Press. 2012 Aug;21(4):211-9. doi: 10.3109/08037051.2012.656395. Epub 2012 Feb 17.
The control of high blood pressure (BP) remains insufficient in developed as well as in developing countries. We conducted a cross-sectional survey to investigate the management of hypertension and the achievement of target BPs in a large population of hypertensive patients treated by Swiss primary care physicians.
Data from 4594 hypertensive patients were collected and assessed for demographic data, mode of treatment and BP achievements for the overall population and for high-risk patients such as diabetics and patients with impaired renal function (CKD patients). Furthermore, we analysed the achieved BP in patients receiving single pill combinations or dual free combinations for the three most commonly prescribed substances.
In this large patient population, 84% of patients were receiving an antihypertensive treatment of which 54% showed BP control (< 140/90 mmHg or < 130/80 mmHg for diabetics and patients with CKD). Considering the higher BP target in the elderly, 60.6% of treated patients were on target. In contrast, 28.8% of treated diabetics and 29.7% of patients with impaired renal function met BP goals. Diuretics and blockers of the renin-angiotensin system were the most commonly prescribed substances. High-risk patients and patients at advanced age (≥ 80 years) received dual free combination more frequently than younger patients. The use of diuretics was particularly high because of the prescription of single pill formulations. Differences in the pattern of drug prescription were found according to the linguistic areas.
The control of hypertension in the Swiss hypertensive population is relatively high but still insufficient particularly among high cardiovascular risk patients such as diabetics and patients with impaired renal function. A further improvement of BP control could perhaps be achieved with a greater use of single pill combinations particularly in patients with complicated hypertension.
在发达国家和发展中国家,高血压(BP)的控制情况仍然不尽人意。我们开展了一项横断面调查,以研究瑞士初级保健医生治疗的大量高血压患者的高血压管理情况及血压控制目标的达成情况。
收集了4594例高血压患者的数据,并对总体人群以及糖尿病患者和肾功能受损患者(慢性肾脏病患者)等高风险患者的人口统计学数据、治疗方式和血压控制情况进行了评估。此外,我们分析了接受三种最常用药物的单片复方制剂或自由联合制剂治疗的患者所达到的血压水平。
在这个庞大的患者群体中,84%的患者正在接受抗高血压治疗,其中54%的患者血压得到控制(糖尿病患者和慢性肾脏病患者的血压控制目标为<140/90 mmHg或<130/80 mmHg)。考虑到老年人的血压目标较高,60.6%接受治疗的患者达到了目标血压。相比之下,28.8%接受治疗的糖尿病患者和29.7%肾功能受损患者达到了血压目标。利尿剂和肾素-血管紧张素系统阻滞剂是最常用的药物。高风险患者和高龄(≥80岁)患者比年轻患者更频繁地接受自由联合制剂治疗。由于单片制剂的处方,利尿剂的使用尤其高。根据语言区域发现了药物处方模式的差异。
瑞士高血压人群的高血压控制率相对较高,但仍然不足,尤其是在糖尿病患者和肾功能受损患者等高心血管风险患者中。通过更多地使用单片复方制剂,特别是在复杂高血压患者中,或许可以进一步改善血压控制情况。