Institute of Urology, London, UK.
BJU Int. 2012 Aug;110(3):304-25. doi: 10.1111/j.1464-410X.2011.10864.x. Epub 2012 Feb 17.
• To review the less common and not widely discussed, but much more serious complications of prostate cancer treatment of: urethral stricture, bladder neck contracture and urorectal fistula. • The treatment options for patients with organ-confirmed prostate cancer include: radical prostatectomy (RP), brachytherapy (BT), external beam radiotherapy (EBRT), high-intensity focussed ultrasound (HIFU) and cryotherapy; with each method or combination of methods having associated complications. • Complications resulting from RP are relatively easy to manage, with rapid recovery and return to normal activities, and usually a return to normal bodily functions. • However, after non-surgical treatments, i.e. BT, EBRT, HIFU and cryotherapy, these same problems are more difficult to treat with a much slower return to a much lower level of function. • When counselling patients about the primary treatment of prostate cancer they should be advised that although the same type of complication may occur after surgical or non-surgical treatment, the scope and scale of that complication, the ease with which it is treated and the degree of restoration of normality after treatment, is altogether in favour of surgery in those for whom surgery is appropriate and who are fit for surgery.
• 回顾前列腺癌治疗中不太常见且讨论较少,但更严重的并发症:尿道狭窄、膀胱颈挛缩和尿直肠瘘。 • 有器官确认的前列腺癌患者的治疗选择包括:前列腺根治切除术(RP)、近距离放射治疗(BT)、外部束放射治疗(EBRT)、高强度聚焦超声(HIFU)和冷冻治疗;每种方法或联合方法都有相关的并发症。 • RP 引起的并发症相对容易处理,恢复迅速,能迅速恢复正常活动,且通常能恢复正常的身体功能。 • 然而,在非手术治疗后,即 BT、EBRT、HIFU 和冷冻治疗后,这些相同的问题更难处理,恢复到更低水平的功能的速度也更慢。 • 在为前列腺癌的主要治疗方案为患者提供咨询时,应告知他们,尽管手术或非手术治疗后可能会出现相同类型的并发症,但并发症的范围和程度、治疗的难易程度以及治疗后恢复正常的程度,对适合手术且适合手术的患者来说,手术治疗具有优势。