O'Neill S L, Karr T L
Department of Entomology, University of Illinois, Urbana 61801.
Nature. 1990 Nov 8;348(6297):178-80. doi: 10.1038/348178a0.
Cytoplasmic incompatibility (CI) describes the phenomenon whereby eggs fertilized by sperm from insects infected with a rickettsial endosymbiont fail to hatch. Unidirectional CI between conspecific populations of insects is a well documented phenomenon. Bidirectional CI has, however, only been described in mosquito populations, and recently between closely related species of parasitic wasps, where it is of interest as both an unusual form of reproductive isolation and as a potential means of insect population suppression. Here we report on the first known example of bidirectional CI between conspecific populations of Drosophila simulans. Further, we show that defects as early as the first cleavage division are associated with CI. This observation suggests that the cellular basis of CI involves disruption of processes before or during zygote formation and that CI arises from defects in the structure and/or function of the sperm during fertilization.
细胞质不亲和性（CI）描述了这样一种现象：被立克次氏体共生菌感染的昆虫精子使卵子受精后，卵子无法孵化。昆虫同种种群之间的单向细胞质不亲和性是一个有充分文献记载的现象。然而，双向细胞质不亲和性仅在蚊子种群中被描述过，最近在寄生蜂的近缘物种之间也有发现，它作为一种不寻常的生殖隔离形式以及作为抑制昆虫种群的一种潜在手段而备受关注。在此，我们报告了在拟暗果蝇同种种群之间首次发现的双向细胞质不亲和性的已知实例。此外，我们表明早在第一次卵裂时的缺陷就与细胞质不亲和性有关。这一观察结果表明，细胞质不亲和性的细胞基础涉及合子形成之前或期间过程的破坏，并且细胞质不亲和性源于受精过程中精子结构和/或功能的缺陷。
