Gynecologic Oncology Unit, Cancer Center of Excellence "Tommaso Campanella" of Germaneto, Catanzaro, Italy.
Am J Obstet Gynecol. 2012 Aug;207(2):94-100. doi: 10.1016/j.ajog.2012.01.010. Epub 2012 Jan 13.
The aim of the current study was to compare the safety of the laparoscopic vs abdominal approach to staging endometrial cancer. A search was conducted for randomized controlled trials that reported data from women with histologically confirmed endometrial cancer who underwent laparoscopic or abdominal surgery. An additional metaanalysis was performed. The primary endpoints were the rates of intraoperative and postoperative complications. A total of 8 original randomized controlled trials were included in the final analysis. No significant difference was observed in the relative risk (RR) for intraoperative complications between laparoscopy and laparotomy (RR, 1.25; 95% confidence interval, 0.99-1.56; P = .062). In contrast, a significant advantage of laparoscopy over laparotomy was obtained in terms of postoperative complications (RR, 0.71; 95% confidence interval, 0.63-0.79; P = .016). In comparison with abdominal surgery, the safety of the laparoscopic approach for surgical staging of endometrial cancer is similar in terms of intraoperative complications but results in fewer postoperative complications.
本研究旨在比较腹腔镜与经腹途径在子宫内膜癌分期中的安全性。检索了报道经组织学证实患有子宫内膜癌并接受腹腔镜或剖腹手术的女性数据的随机对照试验。还进行了一项荟萃分析。主要终点是术中及术后并发症的发生率。共有 8 项原始随机对照试验被纳入最终分析。腹腔镜与剖腹手术相比，术中并发症的相对风险（RR）无显著差异（RR，1.25；95%置信区间，0.99-1.56；P =.062）。相比之下，腹腔镜在术后并发症方面具有显著优势（RR，0.71；95%置信区间，0.63-0.79；P =.016）。与腹部手术相比，腹腔镜手术在子宫内膜癌手术分期方面的安全性在术中并发症方面相似，但术后并发症更少。
