抗 CD20 治疗川崎病耐药。
Resistant Kawasaki disease treated with anti-CD20.
机构信息
Unité de Médecine Infantile, CHU Timone Enfants, Marseille, France.
出版信息
J Pediatr. 2012 May;160(5):875-6. doi: 10.1016/j.jpeds.2012.01.018. Epub 2012 Feb 17.
PMID:22341587
Abstract
We report the case of a 6-year-old boy who had Kawasaki disease resistant to intravenous immunoglobulin and systemic steroids. Because of an uncontrolled disease course, with significant lesions of the coronary arteries, anti-CD20 treatment was used. Rapid clinical, biological, and cardiac improvement was observed. The patient tolerated the treatment well.
摘要
我们报告了一例对静脉注射免疫球蛋白和全身类固醇治疗抵抗的川崎病 6 岁男孩病例。由于疾病过程不受控制，冠状动脉有明显损伤，因此使用了抗 CD20 治疗。观察到快速的临床、生物学和心脏改善。患者对治疗耐受良好。
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