Nelemans P J, Rampen F H
Katholieke Universiteit, Faculteit der Geneeskunde, Instituut voor Sociale Geneeskunde, Sectie Epidemiologie, Nijmegen.
Ned Tijdschr Geneeskd. 1990 Oct 20;134(42):2038-42.
A study of the mortality rates of cutaneous malignant melanoma over the period 1950-1985 in The Netherlands showed a fourfold increase of mortality. An analysis by birth cohort suggests a cohort effect: age-specific mortality rates increase with successively younger generations. To determine the incidence of malignant melanoma of the skin data were derived from a registration of histological diagnoses of diseases (PALGA). The estimated numbers of new cases of melanoma of the skin were 1270 and 1372 in the years 1986 and 1987 respectively. Data on the trend in incidence are restricted, but indicate an increase. This descriptive study allows no conclusions about the cause of the rise in incidence and mortality rates.
一项针对1950年至1985年期间荷兰皮肤恶性黑色素瘤死亡率的研究显示，死亡率增长了四倍。按出生队列进行的分析表明存在队列效应：特定年龄死亡率随着代际越来越年轻而上升。为确定皮肤恶性黑色素瘤的发病率，数据源自疾病组织学诊断登记处（PALGA）。1986年和1987年皮肤黑色素瘤新发病例估计数分别为1270例和1372例。关于发病率趋势的数据有限，但显示出上升趋势。这项描述性研究无法就发病率和死亡率上升的原因得出结论。
