Department of Medicine, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, Saudi Arabia.
J Infect Public Health. 2012 Mar;5(1):109-11. doi: 10.1016/j.jiph.2011.10.002. Epub 2011 Dec 4.
Rhinocerebral or sinopulmonary mucromycosis is a well-recognized human fungal infection found among immunocompromised and diabetic patients. However, the infection is rare among immunocompetent hosts. We are reporting the case of an adult immunocompetent male patient working as an air-conditioning technician. The patient was a victim of a road traffic accident (RTA) and sustained multiple fractures in the proximal part of the left tibia, distal femur, and scapula. Two weeks postoperatively, Rhizopus microspores were isolated from an infected traumatic wound over the distal femur. Surgical debridement was performed, and the patient was started on amphotericin B. Occupational exposure history and workplace environmental sanitation are crucial for the prevention of this potentially fatal yet preventable infection.
鼻脑型或鼻肺型毛霉菌病是一种公认的人类真菌感染,常见于免疫功能低下和糖尿病患者中。然而,这种感染在免疫功能正常的宿主中较为罕见。我们报告了一例作为空调技术员的成年免疫功能正常男性患者的病例。该患者是道路交通意外(RTA)的受害者,左胫骨近端、股骨远端和肩胛骨多处骨折。术后 2 周,从股骨远端感染性创伤伤口中分离出微小根毛霉孢子。进行了手术清创,并开始使用两性霉素 B 治疗。职业接触史和工作场所环境卫生对于预防这种潜在致命但可预防的感染至关重要。