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当前吸烟与既往吸烟在焦虑和心境障碍与尼古丁依赖的关系中起作用吗?

Does current versus former smoking play a role in the relationship between anxiety and mood disorders and nicotine dependence?

机构信息

Department of Psychology, The University of Vermont, John Dewey Hall, 2 Colchester Ave., Burlington, VT 05405, United States.

出版信息

Addict Behav. 2012 May;37(5):682-5. doi: 10.1016/j.addbeh.2012.01.014. Epub 2012 Jan 25.

DOI:10.1016/j.addbeh.2012.01.014
PMID:22342203
Abstract

OBJECTIVE

Research suggests an association between nicotine dependence and anxiety/mood disorders. Yet, less is known about the role of current versus former smoking in the association between nicotine dependence and these psychiatric disorders. The purpose of the present study was to investigate the relations between anxiety/mood disorders and 1) nicotine dependence and 2) current versus former smoking.

METHOD

Data were drawn from the 2001-2002 National Epidemiologic Survey of Alcohol and Related Conditions, a nationally representative sample of over 43,000 adults in the United States. Analyses examined whether dependent versus non-dependent smoking and current versus former smoking were associated with anxiety/mood disorders.

RESULTS

Current dependent, but not non-dependent, smoking was associated with significantly increased odds of anxiety/mood disorders. There was no association between anxiety/mood disorders and former dependent smoking, compared with never smoking. However, compared with never smoking, former non-dependent smoking was associated with significantly decreased odds of current anxiety/mood disorders.

CONCLUSIONS

Current dependent smoking was positively associated with current anxiety/mood disorders, and former non-dependent smoking was negatively associated with current anxiety/mood disorders. The present research is important for understanding the relation between nicotine dependence and anxiety/mood disorders, and why it may be difficult for people with these disorders to quit smoking. The results from this study indicate that greater clinical attention could be directed toward the role of anxiety/mood disorders in smoking cessation.

摘要

目的

研究表明,尼古丁依赖与焦虑/情绪障碍之间存在关联。然而,对于当前吸烟和曾经吸烟在尼古丁依赖与这些精神疾病之间的关联中的作用,了解较少。本研究的目的是调查焦虑/情绪障碍与 1)尼古丁依赖和 2)当前吸烟与曾经吸烟之间的关系。

方法

数据来自于 2001-2002 年美国全国酒精和相关条件流行病学调查,这是一项对超过 43000 名美国成年人的全国代表性样本的调查。分析检查了依赖型与非依赖型吸烟以及当前吸烟与曾经吸烟是否与焦虑/情绪障碍有关。

结果

当前依赖型吸烟,但非依赖型吸烟,与焦虑/情绪障碍的发生几率显著增加有关。与从不吸烟相比,曾经依赖型吸烟与焦虑/情绪障碍之间没有关联。然而,与从不吸烟相比,曾经非依赖型吸烟与当前焦虑/情绪障碍的发生几率显著降低有关。

结论

当前依赖型吸烟与当前焦虑/情绪障碍呈正相关,而曾经非依赖型吸烟与当前焦虑/情绪障碍呈负相关。本研究对于理解尼古丁依赖与焦虑/情绪障碍之间的关系以及为什么这些障碍患者戒烟困难具有重要意义。这项研究的结果表明,应该更加关注焦虑/情绪障碍在戒烟中的作用。

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