Department of Environmental Engineering, Wuhan University, Wuhan 430079, China.
Chemosphere. 2012 May;87(6):614-20. doi: 10.1016/j.chemosphere.2012.01.036. Epub 2012 Feb 17.
The removal of antibiotic tetracycline (TC) from water by electrochemical advanced oxidation process (EAOP) was performed using a carbon-felt cathode and a DSA (Ti/RuO(2)-IrO(2)) anode. The influence of applied current, initial pH and initial TC concentration on TC removal efficiency was investigated. Response surface methodology (RSM) based on Box-Behnken statistical experiment design (BBD) was applied to analyze the experimental variables. The positive and negative effects of variables and the interaction between variables on TC removal efficiency were determined. The applied current showed positive effect, while the initial pH value and initial tetracycline concentration gave negative effect on TC removal. The interaction between applied current and initial pH value was significant, while the interactions of initial TC concentration with applied current or initial pH were not pronounced. The results of adequacy check confirmed that the proposed models were accurate and reliable to analyze the variables of EAOP. The reaction intermediates were identified by high-performance liquid chromatography-mass spectrometry (LC-MS) technique and a plausible degradation pathway for tetracycline degradation was proposed. The acute toxicity experiments illustrated that the Daphnia magna immobilization rate reached the maximum after 240 min of electrolysis and then decreased with the progress of the reaction.
采用碳纤维毡阴极和 DSA（Ti/RuO2-IrO2）阳极，通过电化学高级氧化工艺（EAOP）去除水中的抗生素四环素（TC）。考察了施加电流、初始 pH 值和初始 TC 浓度对 TC 去除效率的影响。基于 Box-Behnken 统计实验设计（BBD）的响应面法（RSM）用于分析实验变量。确定了变量的正负效应以及变量之间的相互作用对 TC 去除效率的影响。施加电流呈正效应，而初始 pH 值和初始四环素浓度对 TC 去除呈负效应。施加电流和初始 pH 值之间的相互作用显著，而初始 TC 浓度与施加电流或初始 pH 值之间的相互作用不明显。充分性检验的结果证实，所提出的模型能够准确可靠地分析 EAOP 的变量。通过高效液相色谱-质谱联用（LC-MS）技术鉴定了反应中间体，并提出了四环素降解的可能途径。急性毒性实验表明，电解析出 240 min 后，大型溞的固定率达到最大值，然后随着反应的进行而降低。
