Byrdine F. Lewis School of Nursing, Georgia State University, P.O. Box 4019, Atlanta, GA 30302-4019, USA.
Soc Sci Med. 2012 Apr;74(7):958-65. doi: 10.1016/j.socscimed.2011.12.030. Epub 2012 Feb 2.
This U.S.A.-based study examined the quantitative and qualitative characteristics of sleep, as well as the role of sleep, in the association of stress with depression, fatigue, and health-related quality of life (H-QOL) among mothers with a low-birth-weight, preterm infant in the neonatal intensive care unit at early postpartum. Fifty-five first-time mothers kept a sleep diary and filled out a battery of questionnaires. The wrist actigraphy method was also applied to collect information on maternal sleep. We tested a path model, with sleep disturbance and depression mediating the effect of stress on health-related well-being. Results showed that the majority of the study participants were stressed, depressed, fatigued, and at risk for poor physical and mental health. Poor sleep quality as perceived by mothers was significantly associated with their stress, fatigue, and poor mental and physical H-QOL. A cascading effect was found in the path model where maternal stress contributed to poor sleep quality and depression, which in turn contributed to poor mental H-QOL. In addition, poor sleep quality was associated with fatigue, which in turn contributed to poor physical and mental H-QOL. The underlying neurobiological mechanisms through which sleep affects the stress-health relation are discussed. The implications of sleep for intervention and prevention are also addressed.
这项基于美国的研究考察了睡眠的数量和质量特征，以及睡眠在压力与抑郁、疲劳和与健康相关的生活质量（H-QOL）之间关联中的作用，这些与新生儿重症监护病房中出生体重低、早产儿的母亲有关。55 位初为人母的母亲记录了睡眠日记并填写了一系列问卷。腕部动作记录仪方法也用于收集有关产妇睡眠的信息。我们测试了一个路径模型，其中睡眠障碍和抑郁作为压力对健康相关幸福感影响的中介因素。结果表明，大多数研究参与者都承受着压力、抑郁、疲劳，并且存在身心健康不良的风险。母亲感知到的睡眠质量差与她们的压力、疲劳和较差的心理和生理 H-QOL 显著相关。在路径模型中发现了一个级联效应，即母亲的压力导致睡眠质量差和抑郁，进而导致较差的心理 H-QOL。此外，睡眠质量差与疲劳有关，而疲劳又会导致身心 H-QOL 较差。讨论了睡眠影响压力-健康关系的潜在神经生物学机制。还讨论了睡眠对干预和预防的意义。
