Hernandez R J, Poznanski A W, Hopwood N J
AJR Am J Roentgenol. 1979 Sep;133(3):405-8. doi: 10.2214/ajr.133.3.405.
Hypothyroidism affects linear growth less than it affects skeletal maturation, while hypopituitarism linear growth is more severely affected. By determining the mean age for the length of the second metacarpal and dividing by the skeletal age, a ratio R was obtained in 15 hypothyroid children and in 33 with hypopituitarism. R was more than 1 in most hypothyroids and less than 1 in most children with hypopituitarism. Thus, a distinction between these two entities can be made simply from a hand radiograph and appropriate reference sources for determining second metacarpal length age and skeletal age.
甲状腺功能减退对线性生长的影响小于对骨骼成熟的影响，而垂体功能减退对线性生长的影响更为严重。通过确定第二掌骨长度的平均年龄并除以骨骼年龄，在15名甲状腺功能减退儿童和33名垂体功能减退儿童中获得了一个比值R。大多数甲状腺功能减退患者的R大于1，而大多数垂体功能减退儿童的R小于1。因此，仅通过手部X光片以及用于确定第二掌骨长度年龄和骨骼年龄的适当参考资料，就可以区分这两种情况。
