CIMO/Escola Superior Agrária, Instituto Politécnico de Bragança, Campus de Santa Apolónia, Apartado 1172, 5301-855 Bragança, Portugal.
Food Chem Toxicol. 2012 May;50(5):1576-82. doi: 10.1016/j.fct.2012.02.004. Epub 2012 Feb 11.
Crataegus monogyna, Cytisus multiflorus, Malva sylvestris and Sambucus nigra have been used as important medicinal plants in the Iberian Peninsula since a long time ago, and are claimed to have various health benefits. This study aimed to determine the phenolic profile and composition of wild medicinal flowers of those species. The analysis was performed by HPLC-DAD-ESI/MS. Flavonoids, and particularly flavonols and flavones, were the main groups in almost all the studied samples. C. multiflorus sample gave the highest levels of total flavonoids (54.5 mg/gdw), being a chrysin derivative the most abundant flavone found (22.3 mg/gdw). C. monogyna revealed the highest concentration in phenolic acids (5.5 mg/gdw) that were not found in C. multiflorus sample; 5-O-caffeoylquinic acid was the most abundant phenolic acid found in the first species, being a procyanidin trimer also found (1.4 mg/gdw). Kaempferol-3-O-rutinoside (0.84 mg/gdw) and quercetin-3-O-rutinoside (14.9 mg/gdw) were the main flavonols present in M. sylvestris and S. nigra, respectively. Due to the well established antioxidant activity of phenolic compounds, the studied wild medicinal flowers could be selected for processing extracts with health-promoting properties or to be incorporate into functional beverages or products with bioactive properties related to oxidative stress.
锦鸡儿、多花荆豆、野锦葵和黑接骨木长期以来一直被用作伊比利亚半岛的重要药用植物，据称具有多种健康益处。本研究旨在确定这些物种野生药用花的酚类成分和组成。采用 HPLC-DAD-ESI/MS 进行分析。在几乎所有研究的样品中，类黄酮，特别是黄酮醇和黄酮，都是主要成分。多花荆豆样品的总类黄酮含量最高（54.5mg/gdw），其中最丰富的黄酮是白杨素衍生物（22.3mg/gdw）。锦鸡儿中发现的酚酸含量最高（5.5mg/gdw），而在多花荆豆样品中未发现；在第一种植物中发现的最丰富的酚酸是 5-O-咖啡酰奎宁酸，也发现了原花青素三聚体（1.4mg/gdw）。野锦葵和黑接骨木中的主要类黄酮醇分别为山奈酚-3-O-芸香糖苷（0.84mg/gdw）和槲皮素-3-O-芸香糖苷（14.9mg/gdw）。鉴于酚类化合物具有良好的抗氧化活性，这些研究的野生药用花可被选择加工具有促进健康特性的提取物，或添加到具有与氧化应激相关的生物活性特性的功能性饮料或产品中。
