Yamaguchi F, Takahashi H, Okada T, Yajima K, Nakazawa S
Department of Neurosurgery, Nippon Medical School, Tokyo, Japan.
No Shinkei Geka. 1990 Oct;18(10):963-7.
A case of intracranial hypoglossal neurinoma without hypoglossal nerve palsy is reported. A 43-year-old housewife was admitted to our hospital with vertigo and left occipital headache. Neurologically, no cranial nerve deficits were present. CT scan and cerebral angiography showed a mass in the lower left posterior fossa. MRI also revealed a well circumscribed extra-axial mass compressing brain stem and cerebellum to the right. Left suboccipital craniotomy was performed and the tumor was removed subtotally. From the operative findings, the 8th to 11th cranial nerves were not related to the tumor, however, the origin of the tumor was not confirmed. The histology showed Antoni A type neurinoma mixed partially with Antoni B type. After the operation, the tongue deviation appeared to the left, but no other cranial nerve deficit was noticed. Post-operative neuroradiological reexaminations defined slight enlargement of the hypoglossal canal. Then, we concluded that the origin of the tumor must have been the hypoglossal nerve. Most intracranial hypoglossal neurinoma grow in the hypoglossal canal followed by enlargement or erosion of the hypoglossal canal. The author thought that this case suggests that this hypoglossal neurinoma originated from a few rootlets of hypoglossal nerve and grew mainly between the medulla and the hypoglossal canal.
报告了一例无舌下神经麻痹的颅内舌下神经鞘瘤病例。一名43岁家庭主妇因眩晕和左枕部头痛入院。神经系统检查未发现颅神经功能缺损。CT扫描和脑血管造影显示左后颅窝下部有一肿块。MRI也显示一个边界清晰的轴外肿块,将脑干和小脑向右压迫。行左枕下开颅术,肿瘤次全切除。从手术所见来看,第8至11对颅神经与肿瘤无关,但肿瘤起源未得到证实。组织学显示为Antoni A型神经鞘瘤,部分混合有Antoni B型。术后出现向左舌偏斜,但未发现其他颅神经功能缺损。术后神经影像学复查发现舌下神经管略有扩大。然后,我们得出结论,肿瘤起源必定是舌下神经。大多数颅内舌下神经鞘瘤生长于舌下神经管,随后舌下神经管扩大或侵蚀。作者认为该病例提示此舌下神经鞘瘤起源于舌下神经的几根神经根,主要生长于延髓和舌下神经管之间。