Serizawa T, Yamaura A, Osato K, Nakamura T, Mine S
Department of Neurosurgery, Chiba University, School of Medicine, Japan.
No Shinkei Geka. 1989 Mar;17(3):279-83.
A case of intracranial hypoglossal neurinoma was reported and the literature was reviewed. A 56-year-old female with a three month history of urinary incontinence, headache and gait disturbance was admitted to our hospital in April, 1986. General physical examination revealed nothing remarkable. Café au lait spot was not found. Neurological examination revealed horizontal gaze nystagmus toward the right, paresthesia of the left upper extremity and mild muscle weakness of the left upper and lower extremities. Atrophy of the right side of the tongue with fasciculation was also noted. Computed tomography (plain, enhanced and metrizamide cisternography) demonstrated no obvious findings of a mass in the posterior fossa. Anterior-posterior view of skull tomography showed enlargement of the right hypoglossal canal. MRI in short spin echo demonstrated a low intensity mass at the foramen magnum on the right side, which compressed the medulla oblongata. Vertebral angiography demonstrated a hypovascular extra-axial mass with right posterior inferior cerebellar artery displacement. On May 1986, suboccipitocranioectomy was performed. The intracranial tumor which arose from the right hypoglossal nerve was removed, but the extracranial portion of the tumor was left unremoved. Histological diagnosis was neurinoma. Post-operative course was uneventful. Intracranial hypoglossal neurinoma are rare and our case marks the 38th reported case. Hypoglossal nerve palsy is the most important symptom and the enlargement of the hypoglossal canal shown by skull tomography or CT for bone images is the most frequent neuroradiological findings. Plain, enhanced CT and metrizamide CT have been discussed as very useful means to detect this lesion.(ABSTRACT TRUNCATED AT 250 WORDS)
报告了1例颅内舌下神经鞘瘤并对文献进行复习。一名56岁女性,有3个月的尿失禁、头痛和步态障碍病史,于1986年4月入住我院。全身体格检查未见明显异常。未发现咖啡斑。神经系统检查发现右眼水平凝视性眼球震颤、左上肢感觉异常以及左上肢和下肢轻度肌无力。还注意到右侧舌肌萎缩伴肌束震颤。计算机断层扫描(平扫、增强及甲泛葡胺脑池造影)未显示后颅窝有明显肿块。颅骨断层扫描前后位片显示右侧舌下神经管扩大。短自旋回波磁共振成像显示右侧枕大孔处有一低强度肿块,压迫延髓。椎动脉造影显示轴外低血运肿块,伴右小脑后下动脉移位。1986年5月行枕下开颅切除术。切除了起源于右侧舌下神经的颅内肿瘤,但肿瘤的颅外部分未切除。组织学诊断为神经鞘瘤。术后病程平稳。颅内舌下神经鞘瘤罕见,本例为第38例报道病例。舌下神经麻痹是最重要的症状,颅骨断层扫描或CT骨像显示的舌下神经管扩大是最常见的神经放射学表现。平扫、增强CT及甲泛葡胺CT已被认为是检测该病变的非常有用的方法。(摘要截于250字)