Department of Nephrology, General Hospital of the Navy, Second Military Medical University, Beijing, China.
Blood Purif. 2012;33(4):227-37. doi: 10.1159/000336092. Epub 2012 Feb 15.
Continuous renal replacement therapy plays an important role in emergency rescue. Currently, no continuous renal replacement therapy machine can be used under unstable conditions as the fluid flow of these machines is controlled electronically. A novel machine that can provide emergency continuous renal replacement therapy in disaster rescue is therefore needed.
Based on a volumetric metering method, a prototype portable continuous blood purifier based on a volumetric metering method was developed. Basic performance tests, special environmental tests, animal experiments and clinical use of the novel machine were completed to test and verify its performance under unstable conditions.
All tests completed showed that the machine met the requirements of the national industry standards with a size reduced to approximately one half of the Baxter Aquarius machine. The clearance of harmful substances by the machine described here was equal to that of the Baxter Aquarius machine and was adequate for clinical purposes.
The novel prototype performed well in all situations tested and can aid rescue work on disaster sites.
连续肾脏替代疗法在急诊救援中发挥着重要作用。目前，由于这些机器的流体流量是通过电子控制的，因此在不稳定的情况下无法使用任何连续肾脏替代疗法机器。因此，需要一种新型的机器，可以在灾难救援中提供紧急连续肾脏替代疗法。
基于体积计量法，开发了一种基于体积计量法的原型便携式连续血液净化器。对新型机器进行了基本性能测试、特殊环境测试、动物实验和临床使用，以测试和验证其在不稳定条件下的性能。
所有完成的测试均表明，该机器符合国家行业标准的要求，其尺寸缩小到 Baxter Aquarius 机器的约一半。该机器对有害物质的清除率与 Baxter Aquarius 机器相当，足以满足临床需求。
新型原型机在所有测试情况下表现良好，可协助灾难现场的救援工作。
