Department of Endocrinology and Nutrition, Diabetes Unit, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Diabetes Care. 2012 Apr;35(4):774-9. doi: 10.2337/dc11-1679. Epub 2012 Feb 16.
The objective of this study was to analyze the clinical characteristics and levels of glycemic and cardiovascular risk factor control in patients with type 2 diabetes that are in primary health care centers in Catalonia (Spain).
This was a cross-sectional study of a total population of 3,755,038 individuals aged 31-90 years at the end of 2009. Clinical data were obtained retrospectively from electronic clinical records.
A total of 286,791 patients with type 2 diabetes were identified (7.6%). Fifty-four percent were men, mean (SD) age was 68.2 (11.4) years, and mean duration of disease was 6.5 (5.1) years. The mean (SD) A1C value was 7.15 (1.5)%, and 56% of the patients had A1C values ≤7%. The mean (SD) blood pressure (BP) values were 137.2 (13.8)/76.4 (8.3) mmHg, mean total cholesterol concentration was 192 (38.6) mg/dL, mean HDL cholesterol concentration was 49.3 (13.2) mg/dL, mean LDL cholesterol (LDL-C) concentration was 112.5 (32.4) mg/dL, and mean BMI was 29.6 (5) kg/m(2). Thirty-one percent of the patients had BP values ≤130/80 mmHg, 37.9% had LDL-C values ≤100 mg/dL, and 45.4% had BMI values ≤30 kg/m(2). Twenty-two percent were managed exclusively with lifestyle changes. Regarding medicated diabetic patients, 46.9, 22.9, and 2.8% were prescribed one, two, or three antidiabetic drugs, respectively, and 23.4% received insulin therapy.
The results from this study indicate a similar or improved control of glycemia, lipids, and BP in patients with type 2 diabetes when compared with previous studies performed in Spain and elsewhere.
本研究旨在分析 2009 年底在加泰罗尼亚(西班牙)基层医疗保健中心就诊的 2 型糖尿病患者的临床特征和血糖及心血管风险因素控制水平。
这是一项针对总人口为 3755038 人的横断面研究,年龄在 31-90 岁之间。临床数据从电子病历中回顾性获得。
共确定了 286791 例 2 型糖尿病患者(7.6%)。其中 54%为男性,平均(SD)年龄为 68.2(11.4)岁,平均病程为 6.5(5.1)年。平均(SD)A1C 值为 7.15(1.5)%,56%的患者 A1C 值≤7%。平均(SD)血压(BP)值为 137.2(13.8)/76.4(8.3)mmHg,平均总胆固醇浓度为 192(38.6)mg/dL,平均高密度脂蛋白胆固醇浓度为 49.3(13.2)mg/dL,平均低密度脂蛋白胆固醇(LDL-C)浓度为 112.5(32.4)mg/dL,平均 BMI 为 29.6(5)kg/m²。31%的患者 BP 值≤130/80mmHg,37.9%的患者 LDL-C 值≤100mg/dL,45.4%的患者 BMI 值≤30kg/m²。22%的患者仅通过生活方式改变进行治疗。对于接受药物治疗的糖尿病患者,分别有 46.9%、22.9%和 2.8%的患者使用一种、两种或三种降糖药物,23.4%的患者接受胰岛素治疗。
与西班牙和其他地区以往的研究相比,本研究结果表明 2 型糖尿病患者的血糖、血脂和血压控制水平相似或有所改善。