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哌拉西林预防术后感染的临床经验

[Clinical experience with piperacillin in the prophylaxis of post-operative infections].

作者信息

Santi F

机构信息

Divisione di Chirurgia Generale, Ospedale Civile, Saluzzo, Cuneo.

出版信息

Minerva Med. 1990 Oct;81(10):701-5.

PMID:2234465
Abstract

Ninety patients who had undergone surgery have been treated with piperacillin as a prophylaxis for hospital infections. Twenty-two (24.4%) emergency operations and sixty-eight (75.6%) elective ones have been performed. Thirty-five open drainages, seven vacuum drainages and fifty-five urinary catheters have been placed. Post-operative infections occurred in 18 patients (20%), five of them submitted to emergency operations and thirteen submitted to elective operations. In eight cases an open drainage had been placed and in three cases a vacuum rate. The Author concludes that the hospital infections rate agrees with that occurring in the quoted sources; that open drainages, especially if placed through surgical wound, have main responsibilities for infections, and that piperacillin acted as a very well tolerated antibiotic and a highly manageable and effective one, offering therefore a good prophylaxis for hospital infections.

摘要

90例接受手术的患者接受了哌拉西林治疗,作为医院感染的预防措施。其中进行了22例(24.4%)急诊手术和68例(75.6%)择期手术。放置了35根开放引流管、7根负压引流管和55根导尿管。18例患者(20%)发生了术后感染,其中5例接受急诊手术,13例接受择期手术。8例放置了开放引流管,3例放置了负压引流管。作者得出结论,医院感染率与引用资料中的感染率一致;开放引流管,尤其是通过手术伤口放置的,对感染负有主要责任,并且哌拉西林是一种耐受性良好、易于管理且有效的抗生素,因此对医院感染提供了良好的预防作用。

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