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[Morphine addiction in non-human primates using rhesus monkeys].

作者信息

Wu Xu-Jun, Zong Wei, Sun Yong-Mei, Hu Xin-Tian, Ma Yuan-Ye, Wang Jian-Hong

机构信息

Chinese Academy of Sciences, Kunming, China.

出版信息

Dongwuxue Yanjiu. 2012 Feb;33(1):89-91. doi: 10.3724/SP.J.1141.2012.01089.

DOI:10.3724/SP.J.1141.2012.01089
PMID:22345015
Abstract

We showed that rhesus monkeys (Macaca mulatta) can develop a morphine dependence. Rhesus monkeys successfully established a conditioned place preference (CPP) induced by morphine treatment and this preference lasted for at least (36.3 ± 1.3) months. This animal model may be useful for research into addiction in humans.

摘要

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Non-human primate models in drug addiction deserve more attention.药物成瘾方面的非人灵长类动物模型值得更多关注。
Dongwuxue Yanjiu. 2014 May;35(3):172-3. doi: 10.11813/j.issn.0254-5853.2014.3.172.