Maastricht University Medical Center, Maastricht, The Netherlands. Maastricht University, Maastricht, The Netherlands.
Eur J Prev Cardiol. 2013 Feb;20(1):135-41. doi: 10.1177/2047487312437038. Epub 2012 Jan 20.
The 6-minute walk test (6 MWT) is widely used to assess exercise tolerance in cardiac rehabilitation (CR). However, previous research shows it to be insufficiently responsive, especially for patients with a relatively high maximal exercise tolerance at baseline. We therefore designed a 6-minute walk/run test (6 MWRT), which has the same duration as the 6 MWT but allows running. The objective of this study was to determine the test-retest reproducibility and responsiveness of this 6 MWRT.
Responsiveness was investigated in a prospective cohort study among a group of patients entering CR at Maastricht University Medical Center, with a cross-sectional part to assess the test-retest reproducibility.
Test-retest reproducibility (reliability and agreement) was investigated using the intraclass correlation (ICC) and a Bland-Altman plot of two measurements implemented in the first week of rehabilitation. Responsiveness of the 6 MWT and the 6 MWRT was calculated using the standard response mean (SRM) over a 6-week period.
The first reproducibility analysis included 34 patients, the second 22 patients. The ICCs were 0.935 and 0.906, respectively, with limits of agreement of ± 79 and ± 61 m. The responsiveness analysis included 27 patients. The SRM values were 0.83 for the 6 MWT and 0.71 for the 6 MWRT.
Although the 6 MWRT is a reproducible test in CR, its responsiveness is not superior to that of the 6 MWT. We therefore prefer the conventional 6 MWT as an evaluative measurement in CR and advise against using the 6 MWRT as (evaluative) measurement in CR for this purpose.
6 分钟步行测试（6MWT）被广泛用于评估心脏康复（CR）中的运动耐量。然而，之前的研究表明，该测试的反应不够灵敏，特别是对于基线时最大运动耐量相对较高的患者。因此，我们设计了一种 6 分钟步行/跑步测试（6MWRT），其持续时间与 6MWT 相同，但允许跑步。本研究的目的是确定该 6MWRT 的测试-重测可重复性和反应性。
在马斯特里赫特大学医学中心接受 CR 的患者中进行了一项前瞻性队列研究，进行了横断面部分以评估测试-重测的可重复性。
使用两次测量的组内相关系数（ICC）和 Bland-Altman 图来研究测试-重测的可重复性（可靠性和一致性），这两次测量是在康复的第一周进行的。在 6 周的时间内，使用标准反应均值（SRM）计算 6MWT 和 6MWRT 的反应性。
第一次可重复性分析包括 34 名患者，第二次分析包括 22 名患者。ICC 分别为 0.935 和 0.906，一致性界限分别为±79 和±61m。反应性分析包括 27 名患者。6MWT 和 6MWRT 的 SRM 值分别为 0.83 和 0.71。
虽然 6MWRT 在 CR 中是一种可重复的测试，但它的反应性并不优于 6MWT。因此，我们更喜欢将传统的 6MWT 作为 CR 中的评估测量，不建议将 6MWRT 用于此目的的评估测量。
