Kapoor Mukul Chandra, Vakamudi Mahesh
Department of Anaesthesiology, Pushpanjali Crosslay Hospital, Ghaziabad, Uttar Pradesh, India.
J Anaesthesiol Clin Pharmacol. 2012 Jan;28(1):92-100. doi: 10.4103/0970-9185.92455.
The search for an ideal inhalational general anesthetic agent continues. Desflurane, which was recently introduced in the Indian market, possesses favorable pharmacokinetic and pharmacodynamic properties and is closer to the definition of an ideal agent. It offers the advantage of precise control over depth of anesthesia along with a rapid, predictable, and clear-headed recovery with minimal postoperative sequelae, making it a valuable anesthetic agent for maintenance in adults and pediatric patients in surgeries of all durations. The agent has advantages when used in extremes of age and in the obese. Its use may increase the direct costs of providing anesthetic care. Methods or techniques, such as low-flow anesthesia, to reduce the overall cost and along with minimal environmental implications must be followed.
对理想吸入性全身麻醉剂的探索仍在继续。地氟烷最近在印度市场推出，具有良好的药代动力学和药效学特性，更接近理想麻醉剂的定义。它具有精确控制麻醉深度的优势，恢复迅速、可预测且清醒，术后后遗症最少，使其成为各类时长手术中成人和儿童患者维持麻醉的宝贵药物。该药物在老年和肥胖患者使用时具有优势。使用它可能会增加麻醉护理的直接成本。必须采用如低流量麻醉等方法或技术来降低总体成本，并尽量减少对环境的影响。
