Kota Sunil K, Kota Siva K, Meher Lalit K, Tripathy Prabhas R, Sruti Jammula, Modi Kirtikumar D
Department of Endocrinology, Medwin Hospital, Hyderabad, Andhra Pradesh, India.
J Cardiovasc Dis Res. 2012 Jan;3(1):36-9. doi: 10.4103/0975-3583.91601.
Pheochromocytomas have been described to be associated with rare vascular abnormalities, most common of them being renal artery stenosis. A 45-year-old woman was admitted to our hospital with complaints of headache, sweating, anxiety, dizziness, nausea, vomiting and severe hypertension. Hypertension was confirmed to result from both excess catecholamine production and hyperreninemia of left kidney. The technical images (abdominal CT and renal arteriography) revealed the presence of a left adrenal pheochromocytoma and stenosis of the renal artery. Surgical removal of pheochromocytoma and correction of renal artery stenosis restored the postoperative plasma catecholamine, renin and blood pressure to normal. To our belief, this is the first such case report from India citing this rare association. We conclude that when the two diseases occur simultaneously, both must be diagnosed accurately and treated in a different manner. We also hereby review the existing literature.
嗜铬细胞瘤已被描述为与罕见的血管异常有关,其中最常见的是肾动脉狭窄。一名45岁女性因头痛、出汗、焦虑、头晕、恶心、呕吐和严重高血压入院。经证实,高血压是由过量儿茶酚胺分泌和左肾高肾素血症共同引起的。影像学检查(腹部CT和肾动脉造影)显示左肾上腺嗜铬细胞瘤和肾动脉狭窄。手术切除嗜铬细胞瘤并纠正肾动脉狭窄后,术后血浆儿茶酚胺、肾素和血压恢复正常。据我们所知,这是印度首例引用这种罕见关联的病例报告。我们得出结论,当这两种疾病同时发生时,必须准确诊断并采用不同的治疗方法。我们在此还对现有文献进行了综述。