Kundu Sanchita, Pal Mousumi, Paul Ranjan R
Department of Oral and Maxillofacial Pathology, Guru Nanak Institute of Dental Sciences and Research, Panihati, Kolkata, India.
Contemp Clin Dent. 2011 Oct;2(4):390-3. doi: 10.4103/0976-237X.91811.
Chondrosarcoma is a rare primary malignant neoplasm of the head, neck, oral and maxillofacial regions. The clinicopathological and radiographic findings are usually characteristic; however, not decisive. The neoplasm is usually treated by wide surgical resection because it is traditionally radioresistant. However, radiotherapy is generally advised for high-grade lesions, and chemotherapy has a palliative role. The treatment and management are primarily guided by the histological grades of the neoplasm. Prognosis of jaw lesions is poor as compared to the lesions affecting the long bones of the body, and the cause of death is usually by direct extension in the base of the skull or due to distant metastasis to lungs and other bones. A clinical case of chondrosarcoma, involving the right half of mandible of a 36 year old male patient is discussed herewith, encompassing the entire gamut of clinicopathological, radiological and treatment modalities rendered.
软骨肉瘤是头颈部、口腔及颌面区域罕见的原发性恶性肿瘤。其临床病理及影像学表现通常具有特征性，但并非决定性的。由于传统上该肿瘤对放疗不敏感，通常采用广泛手术切除治疗。然而，对于高级别病变一般建议进行放疗，化疗则起姑息作用。治疗和管理主要依据肿瘤的组织学分级。与累及身体长骨的病变相比，颌骨病变的预后较差，死亡原因通常是向颅底直接蔓延或远处转移至肺及其他骨骼。本文讨论了一例36岁男性患者右下颌骨软骨肉瘤的临床病例，涵盖了临床病理、放射学及所采用的治疗方式的全部内容。
