João de Barros Barreto University Hospital, Federal University of Pará, Brazil.
Int J Oral Maxillofac Surg. 2012 Feb;41(2):203-10. doi: 10.1016/j.ijom.2011.10.002. Epub 2011 Nov 3.
Chondrosarcoma (CHS) is a malignant neoplasm characterized by the formation of cartilaginous matrix by neoplastic cells, with a high propensity for local recurrences. Head and neck CHS is rare, accounting for less than 12% of all cases of CHS, usually affecting the maxilla. The majority of affected patients are in the fourth decade of life, with a slight predilection for male patients. A painless swelling is commonly the most frequent complaint. Surgery with wide en-bloc resection is the preferred treatment for CHS; radiotherapy and chemotherapy are usually palliative options. Owing to its rarity, there are few clinical series evaluating the biological behaviour of head and neck CHS. The aim of this study is to analyse the clinicopathological characteristics of head and neck CHS by reporting 3 new cases of this neoplasia affecting the jaw bones and reviewing the clinical series previously published in the English literature.
软骨肉瘤（CHS）是一种恶性肿瘤，其特征是肿瘤细胞形成软骨基质，具有很高的局部复发倾向。头颈部 CHS 较为罕见，占所有 CHS 病例的比例不到 12%，通常累及上颌骨。大多数受影响的患者处于 40 岁出头，男性略多。无痛性肿胀通常是最常见的主诉。广泛整块切除术是 CHS 的首选治疗方法；放疗和化疗通常是姑息性选择。由于其罕见性，很少有临床系列评估头颈部 CHS 的生物学行为。本研究旨在通过报告 3 例新的颌骨 CHS 病例，分析其临床病理特征，并复习以往发表的英文文献中的临床系列。
