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2'-羟甲基-1'-(4-甲基苯基)-2'-硝基-1',2',5',6',7',7a'-六氢-螺[吲哚啉-3,3'-吡咯嗪]-2-酮

2'-Hy-droxy-methyl-1'-(4-methyl-phen-yl)-2'-nitro-1',2',5',6',7',7a'-hexa-hydro-spiro-[indoline-3,3'-pyrrolizin]-2-one.

作者信息

Sathya S, Bhaskaran Sundari, Usha G, Sivakumar N, Bakthadoss M

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o277. doi: 10.1107/S1600536811055449. Epub 2012 Jan 7.

DOI:10.1107/S1600536811055449
PMID:22346919
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3274974/
Abstract

In the title compound, C(22)H(23)N(3)O(4), the tolyl ring is almost perpendicular [83.86 (7)°] to the best plane through the eight atoms of the pyrrolizidine ring system. The mol-ecular conformation is stabilized by an intra-molecular O-H⋯O hydrogen bond. The crystal packing features inversion dimers with R(2) (2)(8) motifs linked by pairs of N-H⋯O hydrogen bonds.

摘要

在标题化合物C₂₂H₂₃N₃O₄中，甲苯基环与通过吡咯里西啶环系统的八个原子的最佳平面几乎垂直[83.86 (7)°]。分子构象通过分子内O—H⋯O氢键得以稳定。晶体堆积的特征是具有R₂²(8) motif的反演二聚体，通过成对的N—H⋯O氢键相连。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bba0/3274974/7efed8f742f5/e-68-0o277-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bba0/3274974/cff2e3f72da6/e-68-0o277-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bba0/3274974/7efed8f742f5/e-68-0o277-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bba0/3274974/cff2e3f72da6/e-68-0o277-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bba0/3274974/7efed8f742f5/e-68-0o277-fig2.jpg

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