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（）-4-[2-（8-羟基喹啉-2-基）乙烯基]苯甲酸甲酯的晶体结构

Crystal structure of methyl ()-4-[2-(8-hy-droxy-quinolin-2-yl)vin-yl]benzoate.

作者信息

Xu Yu-Xing, Hu Wei-Ji, Zhao Guo-Liang

机构信息

College of Chemistry and Life Science, Zhejiang Normal University, Jinhua, Zhejiang 321004, People's Republic of China.

College of Chemistry and Life Science, Zhejiang Normal University, Jinhua, Zhejiang 321004, People's Republic of China; XingZhi College, Zhejiang Normal University, Jinhua, Zhejiang 321004, People's Republic of China.

出版信息

Acta Crystallogr E Crystallogr Commun. 2016 Aug 5;72(Pt 9):1251-1253. doi: 10.1107/S205698901601210X. eCollection 2016 Sep 1.

DOI:10.1107/S205698901601210X
PMID:27920909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5120699/
Abstract

The title compound, CHNO, was synthesized by a Perkin reaction of 2-methyl-8-hy-droxy-quinoline and 4-formyl-2-methyl-benzoate in acetic anhydride under a nitro-gen atmosphere. The mol-ecule has an conformation about the C=C bond, and the quinoline ring system and the benzene ring are inclined to one another by 29.22 (7)°. There is an intra-molecular O-H⋯N hydrogen bond in the 8-hy-droxy-quinoline moiety. In the crystal, mol-ecules are linked by pairs of O-H⋯O hydrogen bonds, forming inversion dimers with an (28) ring motif. The dimers are linked by C-H⋯O hydrogen bonds and C-H⋯π inter-actions, forming sheets parallel to plane (10-1).

摘要

标题化合物CHNO是通过2-甲基-8-羟基喹啉与4-甲酰基-2-甲基苯甲酸酯在乙酸酐中于氮气气氛下进行珀金反应合成的。分子围绕C=C键具有一种构象，喹啉环系统和苯环彼此倾斜29.22 (7)°。在8-羟基喹啉部分存在分子内O-H⋯N氢键。在晶体中，分子通过O-H⋯O氢键对相连，形成具有(28)环模式的反演二聚体。二聚体通过C-H⋯O氢键和C-H⋯π相互作用相连，形成平行于(10-1)平面的片层。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf5/5120699/f0fc78361f7e/e-72-01251-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf5/5120699/1f65d01719a3/e-72-01251-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf5/5120699/91c5df5f544a/e-72-01251-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf5/5120699/f0fc78361f7e/e-72-01251-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf5/5120699/1f65d01719a3/e-72-01251-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf5/5120699/91c5df5f544a/e-72-01251-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bdf5/5120699/f0fc78361f7e/e-72-01251-fig3.jpg

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本文引用的文献

1
The Cambridge Structural Database.剑桥结构数据库。
Acta Crystallogr B Struct Sci Cryst Eng Mater. 2016 Apr;72(Pt 2):171-9. doi: 10.1107/S2052520616003954. Epub 2016 Apr 1.
2
A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells.一种含有 8-羟基喹啉骨架的强效（R）-α-双脂酰衍生物：在 SH-SY5Y 人神经母细胞瘤细胞中其神经保护能力的合成与生物学评价。
Pharmaceuticals (Basel). 2013 Jan 7;6(1):54-69. doi: 10.3390/ph6010054.
3
Oxinobactin and sulfoxinobactin, abiotic siderophore analogues to enterobactin involving 8-hydroxyquinoline subunits: thermodynamic and structural studies.
氧杂诺菌素和磺基氧杂诺菌素，含8-羟基喹啉亚基的肠杆菌素非生物铁载体类似物：热力学和结构研究
Inorg Chem. 2012 Nov 19;51(22):12142-51. doi: 10.1021/ic301081a. Epub 2012 Nov 6.
4
Structure validation in chemical crystallography.化学晶体学中的结构验证
Acta Crystallogr D Biol Crystallogr. 2009 Feb;65(Pt 2):148-55. doi: 10.1107/S090744490804362X. Epub 2009 Jan 20.
5
A short history of SHELX.SHELX简史。
Acta Crystallogr A. 2008 Jan;64(Pt 1):112-22. doi: 10.1107/S0108767307043930. Epub 2007 Dec 21.
6
Fluorogenic Hg2+-selective chemodosimeter derived from 8-hydroxyquinoline.源自8-羟基喹啉的荧光汞离子选择性化学传感器。
Org Lett. 2006 Aug 3;8(16):3413-6. doi: 10.1021/ol060788b.