Rodman Regina E, Willson Thomas D, Connolly Mark M, Podbielski Francis J
Resurrection - St. Joseph Hospital, Department of Surgery, Chicago, Ill., USA.
Case Rep Gastroenterol. 2011 Jan;5(1):1-4. doi: 10.1159/000323681. Epub 2011 Jan 5.
A 48-year-old woman with a history of chronic migraines, initially admitted for inpatient management of intractable migraine headaches, developed new onset abdominal pain, hypotension, and diarrhea on hospital day number ten. In our institution's headache unit, patients are treated by a multidisciplinary approach, including individualized drug therapy based on diagnosis and previous response to therapy. Given the patient's hypotension and clinical appearance, she was transferred to the intensive care unit and treated for septic shock and metabolic acidosis. A bedside colonscopy revealed diffuse ischemic colitis. Final pathology after colon resection showed widespread, transmural necrosis of the colonic wall. We review the pathophysiology of ergotamine use and its potential association with ischemic colitis.
一名48岁有慢性偏头痛病史的女性，最初因顽固性偏头痛入院接受住院治疗，在住院第10天出现新发腹痛、低血压和腹泻。在我们机构的头痛单元，患者采用多学科方法治疗，包括根据诊断和既往治疗反应进行个体化药物治疗。鉴于患者的低血压和临床表现，她被转至重症监护病房，接受感染性休克和代谢性酸中毒的治疗。床边结肠镜检查显示弥漫性缺血性结肠炎。结肠切除术后的最终病理显示结肠壁广泛的透壁坏死。我们回顾了麦角胺使用的病理生理学及其与缺血性结肠炎的潜在关联。
