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[在体内成熟的小鼠卵母细胞在放线菌酮作用下的孤雌激活]

[The parthenogenetic activation under the action of cycloheximide of mouse oocytes matured in vivo].

作者信息

Khamidov D Kh, Koval' T Iu, Shaiunusova D, Goncharova E

出版信息

Ontogenez. 1990 Jul-Aug;21(4):432-5.

PMID:2234796
Abstract

Treatment of mouse oocytes matured in vivo by cycloheximide at a concentration 25 micrograms/ml for 2 h induced female pronucleus formation. In all activated oocytes the formation of the female nucleus was completed 5-6 h after the beginning of cycloheximide treatment. When cycloheximide concentration was decreased down to 5 micrograms/ml, its effect was detected 1 h later as compared with that at a concentration of 25 micrograms/ml.

摘要

用浓度为25微克/毫升的放线菌酮处理体内成熟的小鼠卵母细胞2小时可诱导雌原核形成。在所有激活的卵母细胞中,放线菌酮处理开始后5 - 6小时雌核形成完成。当放线菌酮浓度降至5微克/毫升时,与25微克/毫升浓度相比,1小时后可检测到其作用。

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