Departments of Dermatology Infectology Clinical Laboratory, Pontifical Catholic University of Chile, Santiago, Chile.
Int J Dermatol. 2012 Mar;51(3):283-5. doi: 10.1111/j.1365-4632.2011.04995.x.
Trichophyton mentagrophytes var. erinacei is a zoophilic dermatophyte transmitted by hedgehogs which human infections manifest as highly inflammatory and pruritic eruptions.
We report a 21-year-old woman who presented with a two-week history of a pruritic scaly erythematous plaque on the nose. The patient had kept hedgehogs as pets, and one had bitten her on the tip of the nose two months prior to the appearance of the nasal lesion.
Fungal culture from the scales on the tip of the patient's nose was compatible with T. mentagrophytes var. erinacei. The strains isolated from cultures made from samples taken from the noses and ears of the pet hedgehogs were morphologically similar to the strain isolated from the patient. Morphological identification was confirmed by sequencing the internal transcribed spacer. The lesion was diagnosed as tinea faciei, and therapy was initiated with topical and systemic terbinafine 250mg/day for eight weeks, which resulted in complete improvement.
Trichophyton mentagrophytes var. erinacei is the most common dermatophyte isolated in hedgehogs. Usually T. mentagrophytes var. erinacei infection manifests as an extremely inflammatory and pruritic eruption that is confined to the site of contact with the hedgehog. Although the identification of T. mentagrophytes by traditional methods is possible, identification by ITS region analysis is a fast, simple, and increasingly available method. The increasing frequency of the practice of keeping exotic animals as pets has resulted in the emergence of several zoonotic diseases that can potentially be transmitted to humans.
豚草枝孢霉变种是一种嗜动物真菌，通过刺猬传播，人类感染后表现为高度炎症和瘙痒性皮疹。
我们报告了一名 21 岁的女性，她因鼻子上出现两周的瘙痒性鳞屑红斑而就诊。患者养刺猬当宠物，两个月前，一只刺猬咬了她的鼻尖。
从患者鼻尖鳞屑中培养的真菌与豚草枝孢霉变种相符。从宠物刺猬鼻子和耳朵上采集的样本培养出的菌株与从患者身上分离出的菌株形态相似。通过对内部转录间隔区进行测序，确认了形态学鉴定。病变诊断为面癣，给予特比萘芬 250mg/天局部和全身治疗 8 周，结果完全改善。
豚草枝孢霉变种是从刺猬中分离出的最常见的真菌。通常，豚草枝孢霉变种感染表现为极度炎症和瘙痒性皮疹，仅限于与刺猬接触的部位。虽然传统方法可以鉴定出枝孢霉，但 ITS 区分析是一种快速、简单且越来越普及的方法。饲养异宠作为宠物的做法越来越普遍，导致了几种可能传染给人类的人畜共患病的出现。
