Bahar M, Anavi Y, Abraham A, Ben-Bassat M
Department of Otolaryngology-Head and Neck Surgery, Beilinson Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Petah Tiqva, Israel.
Oral Surg Oral Med Oral Pathol. 1990 Nov;70(5):627-30. doi: 10.1016/0030-4220(90)90412-l.
Reports of primary malignant melanoma arising from the parotid salivary gland are extremely rare and, to date, have been sporadic. We report a pertinent case, and tabulate and correlate the clinical findings of the 13 cases reported thus far in the literature. The most common symptom is a progressively enlarging, asymptomatic, firm, and fixed mass. Total excision has been the established treatment of choice. The contribution of radiotherapy, chemotherapy, and immunotherapy remains unclear, and it is not possible at present to predict the outcome of treatment in individual patients. Although rare, primary malignant melanoma should be considered in the differential diagnosis of parotid tumors. The clinical significance of establishing the diagnosis of primary malignant melanoma of the parotid gland is emphasized.
源自腮腺的原发性恶性黑色素瘤的报告极为罕见,迄今为止一直是散发性的。我们报告一例相关病例,并将文献中迄今报道的13例病例的临床发现进行列表和关联分析。最常见的症状是逐渐增大、无症状、质地坚硬且固定的肿块。根治性切除一直是既定的首选治疗方法。放疗、化疗和免疫治疗的作用仍不明确,目前无法预测个体患者的治疗结果。尽管罕见,但在腮腺肿瘤的鉴别诊断中应考虑原发性恶性黑色素瘤。强调了确立腮腺原发性恶性黑色素瘤诊断的临床意义。