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中线融合缺陷的不恰当手术干预导致继发性脊髓拴系症状:4例自然病史报告的启示

Inappropriate surgical interventions for midline fusion defects cause secondary tethered cord symptoms: implications for natural history report of four cases.

作者信息

Selçuki Mehmet, Umur Ahmet Sükrü, Duransoy Yusuf Kurtulus, Ozdemir Seymen, Selcuki Deniz

机构信息

Neurosurgery Department, Celal Bayar University, Medical School, 1403 sk 5/8 Alsancak, 35220, Izmir, Turkey.

出版信息

Childs Nerv Syst. 2012 Oct;28(10):1755-60. doi: 10.1007/s00381-012-1713-0. Epub 2012 Feb 17.

DOI:10.1007/s00381-012-1713-0
PMID:22349900
Abstract

INTRODUCTION

The causes of tethered spinal cord are various. In order to release the tethering effect of these malformations, the surgical interventions must include removal of all tethering components, reconstruction of the neural tube and sectioning of tight filum terminale as well.

CASES

The cases reported in this paper have had an operation many years before for various developmental defects. After a certain period of time (5-10 years) of the first operation, the patients reapplied to the hospital with various symptoms of spinal cord tethering, either vertical or horizontal.

DISCUSSION

At surgical intervention, it was noted that inappropriate surgical procedures caused retethering of the spinal cord in all patients. Postoperative period of all patients were uneventful. All patients declared relief in their symptoms. We would like to draw attention that untreated (or inappropriately treated) midline developmental defects will invariably cause syndrome of tethered cord. Consequently, prophylactic surgical untethering must be applied to all patients with developmental midline defects as soon as possible.

CONCLUSION

It looks that tethered cord symptoms invariably appear as enough negative influence accumulates as the time passes. Elapsed time may vary but unpleasant end result invariably arrives. While these cases with tethered spinal cord develop progressive neurological symptoms, prophylactic and appropriate surgical intervention should be considered as early as possible. There is no acceptable rationale to wait for the appearance of tethered cord syndrome symptoms to perform surgical untethering of the spinal cord because of the probability of irreversibility of the symptoms (incontinence of urine in particular) of tethered spinal cord syndrome.

摘要

引言

脊髓拴系的病因多种多样。为解除这些畸形的拴系效应,手术干预必须包括切除所有拴系成分、重建神经管以及切断紧张的终丝。

病例

本文报道的病例多年前因各种发育缺陷接受过手术。首次手术后经过一段时间(5 - 10年),患者因脊髓拴系的各种症状再次就医,这些症状既有纵向的也有横向的。

讨论

在手术干预时注意到,所有患者均因不恰当的手术操作导致脊髓再次拴系。所有患者术后恢复顺利。所有患者均称症状缓解。我们想提请注意,未经治疗(或治疗不当)的中线发育缺陷必然会导致脊髓拴系综合征。因此,对于所有有中线发育缺陷的患者,必须尽早进行预防性手术松解。

结论

看起来随着时间推移,当足够多的负面影响积累时,脊髓拴系症状总会出现。时间间隔可能不同,但不愉快的最终结果总会到来。当这些脊髓拴系病例出现进行性神经症状时,应尽早考虑进行预防性和恰当的手术干预。由于脊髓拴系综合征症状(尤其是尿失禁)可能不可逆转,所以没有可接受的理由等待脊髓拴系综合征症状出现后再进行脊髓手术松解。

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本文引用的文献

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2
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3
The timing of primary neurosurgical repair significantly affects neurogenic bladder prognosis in children with myelomeningocele.原发性神经外科修复的时机对脊髓脊膜膨出患儿神经源性膀胱的预后有显著影响。
J Spine Surg. 2019 Sep;5(3):337-350. doi: 10.21037/jss.2019.09.02.
4
Tethered cord syndrome in children: a single-center experience with 162 patients.儿童脊髓拴系综合征:单中心162例患者的经验
Childs Nerv Syst. 2015 Sep;31(9):1559-63. doi: 10.1007/s00381-015-2748-9. Epub 2015 May 22.
5
Cutting filum terminale is very important in split cord malformation cases to achieve total release.在脊髓纵裂畸形病例中,切断终丝对于实现完全松解非常重要。
Childs Nerv Syst. 2015 Mar;31(3):425-32. doi: 10.1007/s00381-014-2586-1. Epub 2014 Dec 3.
J Urol. 2006 Sep;176(3):1161-5. doi: 10.1016/j.juro.2006.04.042.
4
Natural history of tethered cord in patients with meningomyelocele.脊髓脊膜膨出患者终丝紧张的自然病史。
Neurosurgery. 2002 May;50(5):989-93; discussion 993-5. doi: 10.1097/00006123-200205000-00011.
5
Level of conus medullaris in term and preterm neonates.足月儿和早产儿脊髓圆锥的水平。
Arch Dis Child Fetal Neonatal Ed. 1997 Jul;77(1):F67-9. doi: 10.1136/fn.77.1.f67.
6
Surgical treatment supposed natural history of the tethered cord with occult spinal dysraphism.
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7
Pathophysiology of "tethered cord syndrome".“脊髓拴系综合征”的病理生理学
J Neurosurg. 1981 Apr;54(4):494-503. doi: 10.3171/jns.1981.54.4.0494.