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儿童脊髓拴系综合征:单中心162例患者的经验

Tethered cord syndrome in children: a single-center experience with 162 patients.

作者信息

Geyik Murat, Alptekin Mehmet, Erkutlu Ibrahim, Geyik Sırma, Erbas Cem, Pusat Serhat, Kural Cahit

机构信息

Department of Neurosurgery, Gaziantep University, Gaziantep, Turkey,

出版信息

Childs Nerv Syst. 2015 Sep;31(9):1559-63. doi: 10.1007/s00381-015-2748-9. Epub 2015 May 22.

DOI:10.1007/s00381-015-2748-9
PMID:25997405
Abstract

PURPOSE

Tethered cord syndrome (TCS) is not an uncommon clinical problem in children. The aim of this retrospective study is to document our experience on the surgical treatment of TCS in childhood.

METHODS

The data of 162 children who underwent surgical treatment for TCS in a 15-year period were reviewed retrospectively. Their demographic, clinical, radiological, and surgical features were documented. They were divided into two groups as primary and secondary TCS, and the surgical technique for each group was demonstrated. Untethering the spinal cord and correction of the associated malformation were the standard surgical technique for each patient. The results of the treatment were summarized.

RESULTS

Among the 162 children, 101 (62.3%) of them were female and 61 were male with a mean age of 62 months. Primary TCS was detected in 43 patients while secondary TCS was found in 119 (73.4%) patients. Hypertrichosis was the most common physical finding while back pain was the common complaint. Lipoma, split cord malformation, dermal sinus tract, and myelomeningocele were the associated malformations for secondary TCS.

CONCLUSIONS

Children should be individualized for the treatment of TCS. Each patient must be evaluated neurologically and radiologically for the accurate diagnosis. Surgical untethering is the safe and effective method of treatment for children with TCS.

摘要

目的

脊髓栓系综合征(TCS)在儿童中是一个并不罕见的临床问题。这项回顾性研究的目的是记录我们在儿童TCS手术治疗方面的经验。

方法

回顾性分析15年间162例接受TCS手术治疗的儿童的数据。记录他们的人口统计学、临床、放射学和手术特征。将他们分为原发性和继发性TCS两组,并展示每组的手术技术。松解脊髓和矫正相关畸形是每位患者的标准手术技术。总结治疗结果。

结果

162例儿童中,101例(62.3%)为女性,61例为男性,平均年龄62个月。43例患者检测出原发性TCS,119例(73.4%)患者为继发性TCS。多毛症是最常见的体征,背痛是常见主诉。脂肪瘤、脊髓纵裂畸形、皮样窦道和脊髓脊膜膨出是继发性TCS的相关畸形。

结论

儿童TCS的治疗应个体化。每位患者必须进行神经学和放射学评估以准确诊断。手术松解是治疗儿童TCS的安全有效方法。

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A new model of tethered cord syndrome produced by slow traction.一种由缓慢牵引产生的脊髓拴系综合征新模型。
Sci Rep. 2015 Mar 13;5:9116. doi: 10.1038/srep09116.
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Disparities in clinical and economic outcomes in children and adolescents following surgery for tethered cord syndrome in the United States.美国儿童和青少年脊髓拴系综合征手术后临床和经济结果的差异。
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The effect of untethering on urologic symptoms and urodynamic parameters in children with primary tethered cord syndrome.
脊髓拴系综合征的临床分析及伤口愈合手术的基因表达谱分析
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Comparison of Ultrasonographic Findings between Patients with Tethered Cord Syndrome and Healthy Children.脊髓栓系综合征患者与健康儿童的超声表现比较。
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Filum terminale transection in pediatric tethered cord syndrome: a single center, population-based, cohort study of 95 cases.终丝切断术治疗小儿脊髓栓系综合征:95 例单中心、基于人群的队列研究。
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Pediatric tethered cord release: an epidemiological and postoperative complication analysis.小儿脊髓栓系松解术:一项流行病学及术后并发症分析
J Spine Surg. 2019 Sep;5(3):337-350. doi: 10.21037/jss.2019.09.02.
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Tethered cord syndrome with lower back pain and lumbosacral angle increase: case report.伴有下背部疼痛和腰骶角增大的脊髓拴系综合征:病例报告
Childs Nerv Syst. 2020 Jan;36(1):219-221. doi: 10.1007/s00381-019-04347-1. Epub 2019 Aug 13.
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