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儿童中枢神经系统结核:30例病例回顾

Central nervous system tuberculosis in children: a review of 30 cases.

作者信息

Waecker N J, Connor J D

机构信息

Department of Pediatrics (Division of Pediatric Infectious Diseases, Naval Hospital, San Diego, CA 92134-5000.

出版信息

Pediatr Infect Dis J. 1990 Aug;9(8):539-43. doi: 10.1097/00006454-199008000-00002.

DOI:10.1097/00006454-199008000-00002
PMID:2235168
Abstract

The medical records of 30 children with central nervous system tuberculosis (CNS tuberculosis) who were treated between March, 1976, and February, 1989, were reviewed. All had cranial computerized tomography scans at presentation. The mean cerebrospinal fluid leukocyte count was 200/mm3, protein 239 mg/dl, glucose 25 mg/dl and CSF/serum glucose ratio 21%. Mantoux skin tests with 5 tuberculin units were greater than or equal to 10 mm induration in 50%, and chest radiographs were positive in 40% of patients. Hydrocephalus was demonstrated by cranial computerized tomography in all 30 patients (100%). Cranial computerized tomography scan demonstrating hydrocephalus is a sensitive radiographic nervous system tuberculosis and should be part of the early evaluation of children with suspected central nervous system tuberculosis.

摘要

回顾了1976年3月至1989年2月间接受治疗的30例中枢神经系统结核(CNS结核)患儿的病历。所有患儿就诊时均进行了头颅计算机断层扫描。脑脊液白细胞计数平均为200/mm³,蛋白质为239mg/dl,葡萄糖为25mg/dl,脑脊液/血清葡萄糖比值为21%。5单位结核菌素的结核菌素皮肤试验硬结直径大于或等于10mm的患儿占50%,胸部X线片阳性的患儿占40%。30例患儿(100%)经头颅计算机断层扫描均显示有脑积水。头颅计算机断层扫描显示脑积水是神经系统结核的一种敏感影像学表现,应作为疑似中枢神经系统结核患儿早期评估的一部分。

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