Reddy Kavitha K, Brauer Jeremy A, Anolik Robert, Bernstein Leonard, Brightman Lori A, Hale Elizabeth, Karen Julie, Weiss Elliot, Geronemus Roy G
Laser & Skin Surgery Center of New York, New York, NY 10016, USA.
Arch Dermatol. 2012 May;148(5):634-6. doi: 10.1001/archdermatol.2011.3374.
Injection of calcium hydroxylapatite filler may result in nodule formation owing to superficial placement of the filler. Calcium hydroxylapatite nodules are difficult to reverse. Previously reported therapeutic options are limited and include intralesional triamcinolone, massage, needling, and excision, each with inconsistent results or potential for scarring.
We have observed complete resolution of calcium hydroxylapatite nodules after a single treatment with fractional carbon dioxide laser.
A single session of fractional carbon dioxide laser treatment may resolve selected cases of calcium hydroxylapatite nodules. The mechanism of action may involve conversion of the product into tricalcium phosphates which dissolve readily. This novel therapeutic technique may enhance treatment options for a difficult clinical problem.
由于羟基磷灰石填充物放置表浅,注射羟基磷灰石填充物可能导致结节形成。羟基磷灰石结节难以逆转。先前报道的治疗选择有限,包括病灶内注射曲安奈德、按摩、针刺和切除,每种方法的效果都不一致或有形成瘢痕的风险。
我们观察到经单次二氧化碳点阵激光治疗后,羟基磷灰石结节完全消退。
单次二氧化碳点阵激光治疗可能解决部分羟基磷灰石结节病例。其作用机制可能涉及将该产物转化为易溶解的磷酸三钙。这种新的治疗技术可能会增加针对这一棘手临床问题的治疗选择。