Sarabia-Arce S, Salazar-Lindo E, Gilman R H, Naranjo J, Miranda E
Department of Pediatrics, Cayetano Heredia University Hospital, Lima, Peru.
Pediatr Infect Dis J. 1990 Sep;9(9):627-31.
A retrospective, hospital-based case-control study was used to investigate whether there were any clinical characteristics that could distinguish Cryptosporidium parvum-infected children with diarrhea from other non-C. parvum-infected children with diarrhea. Ten percent (24 of 248) of children admitted to a rehydration ward at Cayetano Heredia University Hospital, Lima, Peru, were infected with C. parvum. The 24 patients infected with C. parvum (cases) were matched to an equal number of noninfected patients (controls). C. parvum-infected patients were more likely to be malnourished than were children without this infection (P less than 0.05). Also nosocomial infection caused by C. parvum occurred in three severely malnourished patients, two of whom died. No other clinical or laboratory characteristics were found that would distinguish children with diarrhea caused by C. parvum from other children with diarrhea. In children hospitalized for diarrhea C. parvum infection occurs most frequently in malnourished children.
一项基于医院的回顾性病例对照研究旨在调查是否存在任何临床特征，可将感染微小隐孢子虫的腹泻儿童与其他未感染微小隐孢子虫的腹泻儿童区分开来。在秘鲁利马卡耶塔诺·埃雷迪亚大学医院补液病房收治的儿童中，10%（248例中的24例）感染了微小隐孢子虫。24例感染微小隐孢子虫的患者（病例组）与数量相等的未感染患者（对照组）进行匹配。感染微小隐孢子虫的患者比未感染的儿童更易出现营养不良（P<0.05）。此外，3例严重营养不良的患者发生了由微小隐孢子虫引起的医院感染，其中2例死亡。未发现其他临床或实验室特征可将微小隐孢子虫引起腹泻的儿童与其他腹泻儿童区分开来。在因腹泻住院的儿童中，微小隐孢子虫感染最常发生于营养不良的儿童。
