Chorny Alexander, Lifshits Tova, Kratz Assaf, Levy Jaime, Golfarb Daniel, Zlotnik Alexander, Knyazer Boris
Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva.
Harefuah. 2011 Dec;150(12):906-10, 935.
Diabetic retinopathy is the most common microvascular complication of diabetes. In recent years, there is a dramatic increase in the number of diabetic patients in the Bedouin population in the Negev region.
To analyze the clinical features and find out the incidence and risk factors of diabetic retinopathy of type 2 diabetes patients in the Jewish and Bedouin populations.
Data was collected from the files of 523 patients, who were examined by ophthalmologists at different clinics in southern Israel, and who were not previously diagnosed with diabetic retinopathy until that examination. All the data was analyzed by univariate analysis, and a multivariate model was built to predict the risk to develop diabetic retinopathy, separately for the Jewish and Bedouin population in the Negev.
The average age was 64 +/- 10.3 years in the Jewish population and 58.6 +/- 12 years in the Bedouin population (P < 0.001). Treatment with insulin was administered to 14.5% of the Bedouin population, compared to 5.7% of the Jewish population (P < 0.001). Eye complications (diabetic retinopathy and/or maculopathy) were found in 13.4% of Jews, compared to 22% of Bedouins (P < 0.01). In the multivariate analysis we found 6 predicting factors for the development of diabetic retinopathy in the Jewish population: long duration of diabetes, older age, high HbA1c, insulin treatment, high levels of LDL and creatinine; and 4 predicting factors in the Bedouin population: long duration of diabetes, high HbA1c, insulin treatment and smoking.
The Bedouin population in southern Israel suffers more from retinal diabetic complications compared to Jewish patients. Common risk factors for both populations are long duration of diabetes, high HbA1c and insulin treatment.
糖尿病视网膜病变是糖尿病最常见的微血管并发症。近年来，内盖夫地区贝都因人群中的糖尿病患者数量急剧增加。
分析犹太人和贝都因人群中2型糖尿病患者糖尿病视网膜病变的临床特征，找出其发病率及危险因素。
收集了523例患者的病历资料，这些患者由以色列南部不同诊所的眼科医生进行检查，且在此次检查之前未被诊断为糖尿病视网膜病变。所有数据均进行单因素分析，并建立多变量模型，分别对内盖夫地区的犹太人和贝都因人群发生糖尿病视网膜病变的风险进行预测。
犹太人群的平均年龄为64±10.3岁，贝都因人群的平均年龄为58.6±12岁（P<0.001）。14.5%的贝都因人群接受胰岛素治疗，而犹太人群中这一比例为5.7%（P<0.001）。13.4%的犹太人出现眼部并发症（糖尿病视网膜病变和/或黄斑病变），而贝都因人为22%（P<0.01）。在多变量分析中，我们发现犹太人群中发生糖尿病视网膜病变的6个预测因素：糖尿病病程长、年龄大、糖化血红蛋白水平高、胰岛素治疗、低密度脂蛋白和肌酐水平高；贝都因人群中的4个预测因素：糖尿病病程长、糖化血红蛋白水平高、胰岛素治疗和吸烟。
与犹太患者相比，以色列南部的贝都因人群患糖尿病视网膜并发症的情况更严重。这两个人群的共同危险因素是糖尿病病程长、糖化血红蛋白水平高和胰岛素治疗。
