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空气污染与心肌梗死住院:是否存在潜在的敏感人群?

Air pollution and hospital admissions for myocardial infarction: are there potentially sensitive groups?

机构信息

Department of Healthcare Administration, I-Shou University, Kaohsiung, Taiwan.

出版信息

J Toxicol Environ Health A. 2012;75(4):242-51. doi: 10.1080/15287394.2012.641202.

Abstract

Recent studies showed that air pollution is a risk factor for hospitalization for myocardial infarction (MI). However, there is limited evidence to suggest which subpopulations are at higher risk for MI arising from air pollution. This study was undertaken to examine the modifying effects of specific secondary cardiovascular diagnosis (including hypertension, diabetes, congestive heart failure, and arrhythmias) on the relationship between hospital admissions for MI and exposure to ambient air pollutants. Hospital admissions for MI and ambient air pollution data for Taipei were obtained for the period 1999-2009. The relative risk of hospital admissions for MI was estimated using a case-crossover approach. None of the secondary diagnosis examined showed significant evidence of effect modification. It would appear that the correlation between air pollutant exposure and MI occurrence is not affected by predisposing factors present in other cardiovascular diseases.

摘要

最近的研究表明,空气污染是心肌梗死(MI)住院的一个风险因素。然而,目前的证据有限,无法说明哪些亚人群因空气污染而导致 MI 的风险更高。本研究旨在探讨特定的二级心血管诊断(包括高血压、糖尿病、充血性心力衰竭和心律失常)对心肌梗死住院与暴露于环境空气污染物之间关系的修饰作用。1999 年至 2009 年期间,获得了台北市心肌梗死住院和环境空气污染物的数据。使用病例交叉法估计了心肌梗死住院的相对风险。在所检查的二级诊断中,没有任何一个显示出有显著的修饰作用的证据。似乎暴露于空气污染物与 MI 发生之间的相关性不受其他心血管疾病中存在的诱发因素的影响。

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