Institute of Occupational Safety and Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.
J Toxicol Environ Health A. 2009;72(19):1135-40. doi: 10.1080/15287390903091756.
This study was undertaken to determine whether there was an association between air pollutant levels and increased hospital admissions for myocardial infarction (MI) in Kaohsiung, Taiwan. Hospital admissions for MI and ambient air pollution data for Kaohsiung were obtained for the period 1996-2006. The relative risk of hospital admissions was estimated using a case-crossover approach, controlling for weather variables, day of the week, seasonality, and long-term time trends. In the single-pollutant models, on warm days (>25 degrees C), statistically significant positive associations were found in all pollutants except particulate matter (PM(10)) and sulfur dioxide (SO(2)). On cool days (<25 degrees C), all pollutants were significantly associated with MI admissions except for ozone (O(3)). For the two-pollutant model, O(3) and carbon monoxide (CO) were significant in combination with each of the other four pollutants on warm days. On cool days, nitrogen dioxide (NO(2)) remained statistically significant in all the two-pollutant models. This study provides evidence that higher levels of ambient air pollutants increase the risk of higher frequency of hospital admissions for MI.
本研究旨在探讨台湾高雄市的空气污染水平与心肌梗死(MI)住院人数增加之间是否存在关联。我们获得了高雄市 1996-2006 年期间的 MI 住院和环境空气污染数据。使用病例交叉法估计住院风险比,同时控制天气变量、星期几、季节性和长期时间趋势。在单污染物模型中,在温暖日(>25°C),除了颗粒物(PM10)和二氧化硫(SO2)外,所有污染物与 MI 住院均呈显著正相关。在凉爽日(<25°C),除臭氧(O3)外,所有污染物均与 MI 住院显著相关。对于双污染物模型,在温暖日,O3 和一氧化碳(CO)与其他四种污染物中的每一种结合都具有显著意义。在凉爽日,二氧化氮(NO2)在所有双污染物模型中均保持统计学意义。本研究提供了证据表明,较高水平的环境空气污染物会增加 MI 住院频率增加的风险。