Lim Lik Thai, Tarafdar Sonali, Collins Cian E, Ramamurthi Saraswathi, Ramaesh Kanna
Tennent Institute of Ophthalmology, Glasgow, UK.
Semin Ophthalmol. 2012 Jan-Mar;27(1-2):6-7. doi: 10.3109/08820538.2011.588647.
When Brown-McLean syndrome (BMS) was first described, there was no confocal microscopy to document corneal endothelial status, and it was understood as a disease entity involving a diseased endothelial layer. In the advent of confocal microscopy demonstrating healthy endothelium in BMS within the affected cornea, it can be inferred that BMS is a spectrum of disease ranging from healthy to decompensated corneal endothelium, rather than just a specific disease entity. Here we report a case of BMS with normal healthy corneal endothelium using corneal confocal microscopy. Any patient with BMS should be followed up to observe for any disease progression and should be educated regarding the signs and symptoms of corneal surface problems. Confocal microscopy documentation is a convenient and informative way and should form part of the follow-up of any BMS patient.
当首次描述布朗 - 麦克林综合征（BMS）时，还没有共焦显微镜来记录角膜内皮状况，当时它被理解为一种涉及病变内皮层的疾病实体。随着共焦显微镜显示BMS患者患眼角膜内皮层健康，由此可以推断，BMS是一种从健康到失代偿角膜内皮的疾病谱，而不仅仅是一种特定的疾病实体。在此，我们报告一例经角膜共焦显微镜检查显示角膜内皮正常健康的BMS病例。任何BMS患者都应进行随访以观察疾病进展情况，并应就角膜表面问题的体征和症状对其进行教育。共焦显微镜记录是一种方便且信息丰富的方式，应成为任何BMS患者随访的一部分。
