Kymionis George D, Kontadakis Georgios A
Institute of Vision and Optics, University of Crete, Heraklion, Greece.
Semin Ophthalmol. 2012 Jan-Mar;27(1-2):19-21. doi: 10.3109/08820538.2011.588646.
To present a case of unilateral development of severe corneal vascularization in the eye of a keratoconic patient implanted with Intacs microthin prescription inserts and concurrent bilateral use of rigid gas permeable (RGP) contact lenses.
A 20-year-old male underwent unilateral implantation of Intacs in his right eye for treatment of keratoconus and five years later began the use of RGP contact lens. In the left eye the patient continued the use of RGP contact lens.
Ten years after implantation the patient had developed severe central corneal neovascularization in the eye treated with Intacs implantation that recessed one month after discontinuing contact lens use. In the fellow eye he had developed only mild peripheral neovascularization.
Central corneal vascularization is a possible side-effect in patients treated with both Intacs implantation and RGP contact lens fitting that necessitates long term follow-up of such patients.
报告一例圆锥角膜患者，其一只眼睛植入了Intacs微薄处方插入物，并同时双侧使用硬性透气性（RGP）隐形眼镜，出现了严重角膜血管化的单侧发展情况。
一名20岁男性右眼单侧植入Intacs以治疗圆锥角膜，五年后开始使用RGP隐形眼镜。左眼患者继续使用RGP隐形眼镜。
植入十年后，接受Intacs植入治疗的眼睛出现了严重的中央角膜新生血管，在停止使用隐形眼镜一个月后消退。在另一只眼睛中，仅出现了轻度周边新生血管。
中央角膜血管化是接受Intacs植入和RGP隐形眼镜验配治疗的患者可能出现的副作用，这类患者需要长期随访。
