Tittler Ethan H, Nguyen Pho, Rue Kelly S, Vasconcelos-Santos Daniel V, Song Jonathan C, Irvine John A, Smith Ronald E, Rao Narsing A, Yiu Samuel C
Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
J Ophthalmic Inflamm Infect. 2012 Jun;2(2):81-7. doi: 10.1007/s12348-012-0062-1. Epub 2012 Feb 22.
The purpose of this study was to report outcomes of infectious scleritis after pterygium surgery, managed with antibiotic therapies and early scleral debridement.
Retrospective chart review of 13 consecutive cases of infectious scleritis after pterygium excision between 1999 and 2009 was conducted. Collected data included prior medical and surgical history, latency period between pterygium surgery and presentation of infectious scleritis, culture and histopathologic findings, antibiotic regimen, length of hospital stay, visual acuity before and after treatment, and complications.
Median follow-up was at 14 months. Twelve patients underwent prompt surgical debridement after infectious scleritis diagnosis (median, 2.5 days). Debridement was delayed in one patient. Median hospital stay was 3 days. Best-corrected visual acuity improved in ten patients, remained stable in one patient, and decreased in two patients following treatment. Complications included scleral thinning requiring scleral patch graft (1/13), glaucoma (3/13), and progression to phthisis bulbi (1/13). No patients required enucleation.
In contrast to the generally poor outcomes in the literature, early surgical debridement of pterygium-associated infectious scleritis appears to offer improved prognosis.
本研究旨在报告翼状胬肉切除术后感染性巩膜炎采用抗生素治疗及早期巩膜清创术的治疗结果。
对1999年至2009年间连续13例翼状胬肉切除术后感染性巩膜炎病例进行回顾性病历分析。收集的数据包括既往病史和手术史、翼状胬肉手术至感染性巩膜炎发病的潜伏期、培养及组织病理学检查结果、抗生素治疗方案、住院时间、治疗前后视力以及并发症情况。
中位随访时间为14个月。12例患者在感染性巩膜炎确诊后立即接受了手术清创(中位时间为2.5天)。1例患者清创延迟。中位住院时间为3天。治疗后,10例患者最佳矫正视力提高,1例患者视力稳定,2例患者视力下降。并发症包括巩膜变薄需行巩膜补片移植术(1/13)、青光眼(3/13)以及进展为眼球痨(1/13)。无患者需要眼球摘除术。
与文献中普遍较差的治疗结果不同,翼状胬肉相关感染性巩膜炎的早期手术清创似乎能改善预后。