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胃网膜动脉破裂导致巨细胞动脉炎和显微镜下多血管炎合并腹腔积血的并发病例。

A concomitant case of giant cell arteritis and microscopic polyangiitis with hemoperitoneum by rupture of the gastroepiploic artery.

机构信息

Center for Rheumatic Disease, Iizuka Hospital, Iizuka, Fukuoka, Japan.

出版信息

Mod Rheumatol. 2012 Nov;22(6):934-8. doi: 10.1007/s10165-012-0610-4. Epub 2012 Feb 22.

Abstract

Giant cell arteritis (GCA) mainly involves large-sized arteries, while microscopic polyangiitis (mPA), characterized by pauci-immune necrotizing vasculitis, mainly affects small-sized vessels. We report a very rare concomitant case of GCA diagnosed by temporal artery biopsy and mPA with a high titer of myeloperoxidase antineutrophil cytoplasmic antibody, exacerbation of interstitial pneumonia, and suspected rapidly progressive glomerulonephritis. The patient died by sudden rupture of the gastroepiploic artery (medium-sized vessel), which may have been triggered by GCA and/or mPA.

摘要

巨细胞动脉炎(GCA)主要累及大动脉,而显微镜下多血管炎(mPA)以少免疫性坏死性血管炎为特征,主要影响小血管。我们报告了一例非常罕见的同时发生的 GCA 病例,该病例通过颞动脉活检和 mPA 诊断,mPA 伴有髓过氧化物酶抗中性粒细胞胞质抗体高滴度、间质性肺炎恶化和疑似快速进行性肾小球肾炎。患者因胃网膜动脉(中等大小血管)突然破裂而死亡,这可能是由 GCA 和/或 mPA 引发的。

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