Department of General Surgery, Instituto de Cancerologia, Clínica las Américas, Medellin, Colombia.
J Gynecol Oncol. 2012 Jan;23(1):48-52. doi: 10.3802/jgo.2012.23.1.48. Epub 2012 Jan 9.
To report the clinical presentation and oncologic outcomes of a series of patients who presented with an abdominal or pelvic mass and were diagnosed with a gastrointestinal stromal tumor (GIST).
Data were obtained on all patients who presented with an abdominal or pelvic mass between September 2007 and June 2010 and who were ultimately diagnosed with a GIST. The patients' medical records were reviewed. A literature review was also conducted.
Six patients were identified who met the inclusion criteria. All six patients had a tumor in the intestinal tract arising from the small bowel. The mean tumor size was 12 cm (range, 6 to 22 cm). A complete resection was achieved in five of the six patients. There were no intraoperative complications; one patient had a postoperative complication. Two patients were treated with imatinib after surgery. The mean follow-up time was 32 months (range, 0.3 to 40 months). At the last follow-up, five of the six patients were without any evidence of disease. One patient died of an unrelated hepatic encephalopathy. The incidence in our institution is 3%.
GISTs are uncommon; however, they should be considered in the differential diagnosis of patients presenting with an abdominal or pelvic mass.
报告一组以腹部或盆腔肿块就诊、最终诊断为胃肠道间质瘤(GIST)患者的临床表现和肿瘤学结局。
回顾性分析 2007 年 9 月至 2010 年 6 月期间以腹部或盆腔肿块就诊、最终诊断为 GIST 的所有患者的数据。对患者的病历进行了审查,并进行了文献复习。
符合纳入标准的患者共有 6 例。所有 6 例患者均为小肠来源的肠道肿瘤。肿瘤平均大小为 12cm(范围为 6-22cm)。6 例患者中,5 例肿瘤完整切除,无术中并发症,1 例术后发生并发症。术后 2 例患者接受了伊马替尼治疗。平均随访时间为 32 个月(范围为 0.3-40 个月)。末次随访时,6 例患者中 5 例无疾病证据,1 例患者因与肝性脑病无关的原因死亡。本机构的发病率为 3%。
GIST 较为少见,但在诊断以腹部或盆腔肿块就诊的患者时应考虑到这一疾病。