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胃肠道间质瘤在疑似卵巢癌患者中为偶然发现。

Gastrointestinal stromal tumors as an incidental finding in patients with a presumptive diagnosis of ovarian cancer.

机构信息

Department of General Surgery, Instituto de Cancerologia, Clínica las Américas, Medellin, Colombia.

出版信息

J Gynecol Oncol. 2012 Jan;23(1):48-52. doi: 10.3802/jgo.2012.23.1.48. Epub 2012 Jan 9.

Abstract

OBJECTIVE

To report the clinical presentation and oncologic outcomes of a series of patients who presented with an abdominal or pelvic mass and were diagnosed with a gastrointestinal stromal tumor (GIST).

METHODS

Data were obtained on all patients who presented with an abdominal or pelvic mass between September 2007 and June 2010 and who were ultimately diagnosed with a GIST. The patients' medical records were reviewed. A literature review was also conducted.

RESULTS

Six patients were identified who met the inclusion criteria. All six patients had a tumor in the intestinal tract arising from the small bowel. The mean tumor size was 12 cm (range, 6 to 22 cm). A complete resection was achieved in five of the six patients. There were no intraoperative complications; one patient had a postoperative complication. Two patients were treated with imatinib after surgery. The mean follow-up time was 32 months (range, 0.3 to 40 months). At the last follow-up, five of the six patients were without any evidence of disease. One patient died of an unrelated hepatic encephalopathy. The incidence in our institution is 3%.

CONCLUSION

GISTs are uncommon; however, they should be considered in the differential diagnosis of patients presenting with an abdominal or pelvic mass.

摘要

目的

报告一组以腹部或盆腔肿块就诊、最终诊断为胃肠道间质瘤(GIST)患者的临床表现和肿瘤学结局。

方法

回顾性分析 2007 年 9 月至 2010 年 6 月期间以腹部或盆腔肿块就诊、最终诊断为 GIST 的所有患者的数据。对患者的病历进行了审查,并进行了文献复习。

结果

符合纳入标准的患者共有 6 例。所有 6 例患者均为小肠来源的肠道肿瘤。肿瘤平均大小为 12cm(范围为 6-22cm)。6 例患者中,5 例肿瘤完整切除,无术中并发症,1 例术后发生并发症。术后 2 例患者接受了伊马替尼治疗。平均随访时间为 32 个月(范围为 0.3-40 个月)。末次随访时,6 例患者中 5 例无疾病证据,1 例患者因与肝性脑病无关的原因死亡。本机构的发病率为 3%。

结论

GIST 较为少见,但在诊断以腹部或盆腔肿块就诊的患者时应考虑到这一疾病。

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Gastrointestinal stromal tumors (GIST) related emergencies.胃肠道间质瘤(GIST)相关急症。
Int J Surg. 2014;12(4):269-80. doi: 10.1016/j.ijsu.2014.02.004. Epub 2014 Feb 12.

本文引用的文献

1
Surgical therapy for gastrointestinal stromal tumours of the upper gastrointestinal tract.上消化道胃肠道间质瘤的外科治疗
J Gastrointest Surg. 2009 Jul;13(7):1220-5. doi: 10.1007/s11605-009-0885-8. Epub 2009 Apr 16.
2
Surgery for gastrointestinal stromal tumors of the stomach.胃胃肠道间质瘤的手术治疗
J Gastrointest Surg. 2009 Jul;13(7):1213-9. doi: 10.1007/s11605-009-0872-0. Epub 2009 Apr 9.
4
Gastrointestinal stromal tumor: a clinical overview.胃肠道间质瘤:临床概述
Hematol Oncol Clin North Am. 2009 Feb;23(1):69-78, viii. doi: 10.1016/j.hoc.2008.11.006.

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