Mamoon Nadira, Jaffri Sadaf Ali, Ilahi Fazal, Muzaffar Kamil, Iqbal Yasir, Akhter Noreen, Nasir Humaira, Ahmad Imran Nazir
Department of Histopathology, Shifa International Hospital, Islamabad.
J Pak Med Assoc. 2011 Oct;61(10):1025-7.
Yolk sac tumour is germ cell tumour commonly found in children and infants under three years of age in its pure form with a good prognosis. The commonest location for the yolk sac tumour is gonads i.e. testis and gonads. Yolk sac tumour is rarely reported in extra- gonadal locations. Parapharyngeal space is an uncommon site for mature teratoma and very few cases have been reported in adults and children. Malignant transformation in a mature teratoma in the extragonadal sites has been reported but development of yolk sac tumour has not been reported so far in the world literature. We report to our knowledge, the only and first case of yolk sac tumour arising in a mature teratoma presenting as a parapharyngeal mass in a four year old male child.
卵黄囊瘤是一种生殖细胞肿瘤,常见于3岁以下的儿童和婴儿,其单纯形式预后良好。卵黄囊瘤最常见的部位是性腺,即睾丸和卵巢。卵黄囊瘤在性腺外部位很少见。咽旁间隙是成熟畸胎瘤的罕见部位,成人和儿童中报道的病例很少。性腺外部位成熟畸胎瘤发生恶性转化已有报道,但世界文献中至今尚未报道卵黄囊瘤的发生。据我们所知,我们报告了首例也是唯一一例发生在成熟畸胎瘤中的卵黄囊瘤,该肿瘤表现为一名4岁男童的咽旁肿块。