多药治疗——我们让它变得更糟！来自急症入院病房的横断面研究。
Polypharmacy--we make it worse! A cross-sectional study from an acute admissions unit.
机构信息
Department of General Medicine, Christchurch Hospital, Christchurch, New Zealand.
出版信息
Intern Med J. 2012 Feb;42(2):208-11. doi: 10.1111/j.1445-5994.2011.02690.x.
Although polypharmacy is a major problem in the elderly, very few data have been published from Australasia. We retrospectively audited 68% of elderly patients admitted acutely to our medical unit (n= 424, mean age 80.3 ± 8 years) during a 30-day period (September, 2008). We found that long-term medications increased during hospital stay from 6.6 ± 4 to 7.7 ± 4 (P < 0.001). Adverse drug reactions were responsible for 24 admissions (5.7%). Polypharmacy is made worse by acute admission to hospital.
尽管老年人普遍存在多种用药问题，但来自澳大拉西亚地区的数据却非常有限。我们对在一个月（2008 年 9 月）期间急性入住我院内科的 424 例老年患者（平均年龄 80.3 ± 8 岁）进行了 68%的回顾性审核。我们发现，住院期间长期服用的药物从 6.6 ± 4 种增加到 7.7 ± 4 种（P < 0.001）。药物不良反应导致 24 例患者入院（5.7%）。急性入院使老年人的多种用药问题更加恶化。
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