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比较大麻和可卡因依赖患者的物质使用里程碑。

Comparison of substance use milestones in cannabis- and cocaine-dependent patients.

机构信息

Division on Substance Abuse, New York Psychiatric Institute, New York, New York 10022, USA.

出版信息

J Addict Dis. 2012;31(1):60-6. doi: 10.1080/10550887.2011.642753.

DOI:10.1080/10550887.2011.642753
PMID:22356669
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3308723/
Abstract

OBJECTIVES

To compare the progression of substance use milestones between cocaine- and cannabis-dependent patients.

METHODS

Using data gathered from two separate clinical studies for treatment of cocaine dependence and cannabis dependence, 130 cannabis-dependent and 112 cocaine-dependent individuals were compared on milestones related to their substance use.

RESULTS

In cannabis- vs. cocaine-dependent patients, the mean age of first use, regular use and first treatment contact differed significantly. No statistically significant differences were found between the two groups for other measured milestones.

CONCLUSIONS

These results differ from most epidemiologic studies that suggest cocaine users progress more rapidly to regular use and treatment contact.

摘要

目的

比较可卡因和大麻依赖患者物质使用里程碑的进展情况。

方法

利用来自两个独立的可卡因和大麻依赖治疗临床研究的数据,对 130 名大麻依赖者和 112 名可卡因依赖者的物质使用相关里程碑进行比较。

结果

与可卡因依赖者相比,大麻依赖者首次使用、规律使用和首次治疗接触的平均年龄差异有统计学意义。两组之间在其他测量的里程碑上没有发现统计学上的显著差异。

结论

这些结果与大多数流行病学研究不同,后者表明可卡因使用者更快地进展到规律使用和治疗接触。

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本文引用的文献

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Cannabis withdrawal in the United States: results from NESARC.美国的大麻戒断反应:来自全国酒精与相关状况流行病学调查(NESARC)的结果
J Clin Psychiatry. 2008 Sep;69(9):1354-63. doi: 10.4088/jcp.v69n0902. Epub 2008 Sep 9.
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Cannabis potency and contamination: a review of the literature.大麻效力与污染:文献综述
Addiction. 2008 Jul;103(7):1100-9. doi: 10.1111/j.1360-0443.2008.02230.x. Epub 2008 May 20.
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Male-female differences in the risk of progression from first use to dependence upon cannabis, cocaine, and alcohol.首次使用大麻、可卡因和酒精后,男性与女性在成瘾风险方面的差异。
Drug Alcohol Depend. 2007 Jan 12;86(2-3):191-8. doi: 10.1016/j.drugalcdep.2006.06.003. Epub 2006 Oct 9.
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Different lengths of times for progressions in adolescent substance involvement.青少年物质使用情况进展的不同时长。
Addict Behav. 2006 Jun;31(6):962-83. doi: 10.1016/j.addbeh.2006.03.015. Epub 2006 May 4.
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Lifetime comorbidity of DSM-IV mood and anxiety disorders and specific drug use disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions.《精神疾病诊断与统计手册》第四版中情绪和焦虑障碍与特定药物使用障碍的终生共病情况:来自全国酒精及相关状况流行病学调查的结果
J Clin Psychiatry. 2006 Feb;67(2):247-57. doi: 10.4088/jcp.v67n0211.
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High potency cannabis: the forgotten variable.
Addiction. 2005 Oct;100(10):1558-60; author reply 1560-1. doi: 10.1111/j.1360-0443.2005.01295.x.
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Cannabis potency in Europe.
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Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication.全国共病调查复制研究中12个月内DSM-IV疾病的患病率、严重程度及共病情况。
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