Lazarev V A
Biofizika. 1977 Nov-Dec;22(6):995-8.
It has been shown with electron microscope that the form of the tropocollagen macro-molecule in solution is determined by hydrogen ions concentration. It is proposed that in native collagen fibrils the tropocollagen macromolecules have an unknown before form of rods with the thickened central part. Their length is about 1000 A. The known extended form of the tropocollagen macromolecule (the rod of 2800 A length) is probably transformed to the described form by the folding of the macromolecule. The origin of cross striation of the collagen fibril is discussed.
用电子显微镜已表明，溶液中原胶原蛋白大分子的形态由氢离子浓度决定。有人提出，在天然胶原纤维中，原胶原蛋白大分子具有一种以前未知的、中央部分加厚的棒状形态。它们的长度约为1000埃。原胶原蛋白大分子已知的伸展形态（长度为2800埃的棒状）可能是通过大分子的折叠转变为上述形态的。文中还讨论了胶原纤维横纹的起源。
