Chemistry, University of Southampton, Southampton, Hampshire SO17 1BJ, UK.
Chem Commun (Camb). 2012 Apr 7;48(28):3409-11. doi: 10.1039/c2cc17915f. Epub 2012 Feb 22.
The first total synthesis of (+)-mucosin has been completed allowing assignment of the absolute stereochemistry of the natural product. A zirconium induced co-cyclisation was utilised to install the correct stereochemistry of the four contiguous stereocentres around the unusual bicyclo[4.3.0]nonene core.
（+）-粘菌素的全合成首次完成，确定了天然产物的绝对立体化学构型。利用锆诱导的共环化反应在不常见的双环[4.3.0]壬烯核心的四个连续立体中心上引入正确的立体化学构型。
