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合成免疫调节剂。

Synthetic immunomodulators.

机构信息

Cattedra Malattie Infettive, Dipartimento di Medicina Sperimentale-L'Aquila, Italy.

出版信息

Cytotechnology. 1991 Feb;5(Suppl 1):11-4. doi: 10.1007/BF00736796.

DOI:10.1007/BF00736796
PMID:22358942
Abstract

An effective boosting of the host immunocompetence is possible through synthetic immunomodulators, keeping in mind that they are no panacea for all microbial diseases. No drug is effective on all phases or effector cells of the immune response and it is postulated that in a near future combined therapies will be attempted with antibiotics or anti-cancer agents.

摘要

通过合成免疫调节剂,可以有效地增强宿主的免疫能力,但需注意,它们并非治疗所有微生物疾病的万灵药。没有一种药物对免疫反应的所有阶段或效应细胞都有效,据推测,在不久的将来,将尝试联合抗生素或抗癌药物进行治疗。

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本文引用的文献

1
Surgical adjuvant therapy of large-bowel carcinoma: an evaluation of levamisole and the combination of levamisole and fluorouracil. The North Central Cancer Treatment Group and the Mayo Clinic.大肠癌的手术辅助治疗:左旋咪唑及左旋咪唑与氟尿嘧啶联合应用的评估。北中部癌症治疗组和梅奥诊所。
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Zidovudine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.齐多夫定。对其药效学和药代动力学特性以及治疗效果的综述。
Drugs. 1989 Apr;37(4):408-50. doi: 10.2165/00003495-198937040-00003.
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Inosine pranobex and zidovudine metabolism.
肌苷普拉诺贝和齐多夫定的代谢。
Lancet. 1989 Oct 21;2(8669):977. doi: 10.1016/s0140-6736(89)90982-3.
4
Clinical and immunological assessment in HIV+ subjects receiving inosine-pranobex. A randomised, multicentric study.接受肌苷 pranobex 的 HIV 阳性受试者的临床和免疫学评估。一项随机、多中心研究。
Med Oncol Tumor Pharmacother. 1989;6(1):63-7. doi: 10.1007/BF02985225.
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The efficacy of inosine pranobex in preventing the acquired immunodeficiency syndrome in patients with human immunodeficiency virus infection. The Scandinavian Isoprinosine Study Group.肌苷普拉诺贝预防人类免疫缺陷病毒感染患者获得性免疫缺陷综合征的疗效。斯堪的纳维亚异嘌呤醇研究组。
N Engl J Med. 1990 Jun 21;322(25):1757-63. doi: 10.1056/NEJM199006213222501.