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[儿童和成人的特应性皮炎]

[Atopic dermatitis in children and adults].

作者信息

Lipozencić Jasna, Ljubojević Suzana, Gregurić Sanja

机构信息

Department of Dermatology and Venereology, Zagreb University Hospital Center, Zagreb, Croatia.

出版信息

Acta Med Croatica. 2011;65(2):87-96.

PMID:22359873
Abstract

Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease characterized by itching and typical clinical features, depending on patient age. It is often associated with other atopic diseases such as asthma or allergic rhinitis, resulting from the complex etiology and pathogenesis. It occurs more frequently in people with genetic predisposition for atopic diseases. The intensity and extent of skin lesions (Scoring of Atopic Dermatitis, SCORAD Index) vary significantly among AD patients, depending on whether it is acute or chronic, and there are variations in laboratory parameters, especially immune. In the future, it will be necessary to reach consensus on the new criteria for defining AD instead of the old ones (brought by Hanifin and Rajka 31 years ago). What is needed is effective and safe treatment, and control of the early stages of AD as well as maintaining AD remission. The new therapeutic approach in AD has greatly improved the quality of life of AD patients. As the prevalence of the disease continues to increase, we emphasize the importance of prevention, prompt recognition and optimal treatment of the many patients with AD.

摘要

特应性皮炎(AD)是一种慢性复发性炎症性皮肤病,其特征为瘙痒及取决于患者年龄的典型临床特征。由于病因和发病机制复杂,它常与其他特应性疾病如哮喘或过敏性鼻炎相关联。它在有特应性疾病遗传易感性的人群中更常见。根据是急性还是慢性,AD患者的皮肤病变强度和范围(特应性皮炎评分,SCORAD指数)差异显著,并且实验室参数存在差异,尤其是免疫方面。未来,有必要就定义AD的新标准而非旧标准(31年前由哈尼芬和拉伊卡提出)达成共识。需要的是有效且安全的治疗,以及控制AD的早期阶段并维持AD缓解。AD的新治疗方法极大地改善了AD患者的生活质量。随着该疾病患病率持续上升,我们强调对众多AD患者进行预防、及时识别和优化治疗的重要性。

相似文献

1
[Atopic dermatitis in children and adults].[儿童和成人的特应性皮炎]
Acta Med Croatica. 2011;65(2):87-96.
2
Development of atopic dermatitis during the first 3 years of life: the Copenhagen prospective study on asthma in childhood cohort study in high-risk children.生命最初3年特应性皮炎的发生情况:哥本哈根儿童哮喘前瞻性研究中的高危儿童队列研究
Arch Dermatol. 2006 May;142(5):561-6. doi: 10.1001/archderm.142.5.561.
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Severity scoring of atopic dermatitis: a comparison of two scoring systems.特应性皮炎的严重程度评分:两种评分系统的比较。
Allergol Immunopathol (Madr). 2008 Jul-Aug;36(4):205-11.
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Severity of disease, rather than xerosis, correlates with pruritus in patients with atopic dermatitis.在特应性皮炎患者中,疾病的严重程度而非皮肤干燥与瘙痒相关。
Int J Dermatol. 2009 Apr;48(4):374-8. doi: 10.1111/j.1365-4632.2009.03906.x.
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Genetic, Clinical, and Environmental Factors Associated With Persistent Atopic Dermatitis in Childhood.遗传、临床和环境因素与儿童持续性特应性皮炎相关。
JAMA Dermatol. 2019 Jan 1;155(1):50-57. doi: 10.1001/jamadermatol.2018.4061.
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Atopic dermatitis.特应性皮炎
Med Clin North Am. 2006 Jan;90(1):149-67, ix. doi: 10.1016/j.mcna.2005.09.002.
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Scoring atopic dermatitis in infants and young children: distinctive features of the SCORAD index.婴幼儿特应性皮炎的评分:SCORAD指数的显著特征。
Allergy. 2005 Jan;60(1):113-6. doi: 10.1111/j.1398-9995.2004.00622.x.
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Use of textiles in atopic dermatitis: care of atopic dermatitis.纺织品在特应性皮炎中的应用:特应性皮炎的护理
Curr Probl Dermatol. 2006;33:127-43. doi: 10.1159/000093940.
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Diagnostic criteria for atopic dermatitis in Thai children.泰国儿童特应性皮炎的诊断标准。
J Med Assoc Thai. 2004 Dec;87(12):1496-500.
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The treatment of atopic dermatitis and other dermatoses with leukotriene antagonists.白三烯拮抗剂治疗特应性皮炎和其他皮肤病
Skin Therapy Lett. 2004 Feb;9(2):1-5.

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