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高胆固醇饮食喂养大鼠的膳食纤维与胆固醇代谢

Dietary fiber and cholesterol metabolism in rats fed a high cholesterol diet.

作者信息

Jayakumari N, Kurup P A

出版信息

Atherosclerosis. 1979 May;33(1):41-7. doi: 10.1016/0021-9150(79)90196-5.

Abstract

The effect of administering blackgram (Phaseolus mungo) fiber (isolated as neutral detergent residue) at the 30% dietary level has been studied with regard to lipid concentration in the tissues and that of biliary and fecal bile acids and sterols. Rats were fed a high fat-cholesterol diet and compared with those fed a cellulose diet. The results indicate that blackgram fiber significantly lowers cholesterol in both serum and aorta [11]. There was an increased concentration of biliary sterols and bile acids and increased fecal excretion of sterols and bile acids, each of these effects being significantly greater than those observed in the rats fed cellulose.

摘要

已研究了在日粮中添加30%的黑吉豆(绿豆)纤维(作为中性洗涤剂残渣分离出来)对组织中脂质浓度以及胆汁和粪便中胆汁酸和固醇的影响。给大鼠喂食高脂肪高胆固醇饮食,并与喂食纤维素饮食的大鼠进行比较。结果表明,黑吉豆纤维能显著降低血清和主动脉中的胆固醇[11]。胆汁中的固醇和胆汁酸浓度增加,固醇和胆汁酸的粪便排泄量增加,这些影响均显著大于喂食纤维素的大鼠。

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